Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2168606..2169132 Replicon chromosome
Accession NZ_CP021110
Organism Bordetella genomosp. 9 strain AU14267

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CAL14_RS10075 Protein ID WP_086057361.1
Coordinates 2168854..2169132 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CAL14_RS10070 Protein ID WP_086057360.1
Coordinates 2168606..2168821 (+) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAL14_RS10050 2164696..2165337 + 642 WP_086057356.1 response regulator transcription factor -
CAL14_RS10055 2165488..2166261 + 774 WP_198297760.1 helix-turn-helix domain-containing protein -
CAL14_RS10060 2166350..2167780 + 1431 WP_157664449.1 hypothetical protein -
CAL14_RS10065 2167758..2168501 - 744 WP_086057359.1 phosphoribosyltransferase -
CAL14_RS10070 2168606..2168821 + 216 WP_086057360.1 antitoxin Antitoxin
CAL14_RS10075 2168854..2169132 + 279 WP_086057361.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CAL14_RS10080 2169172..2169876 - 705 WP_086057362.1 GntR family transcriptional regulator -
CAL14_RS10085 2170015..2171745 + 1731 WP_086057363.1 dihydroxy-acid dehydratase -
CAL14_RS10090 2171805..2172560 + 756 WP_086057364.1 ribonuclease activity regulator RraA -
CAL14_RS10095 2172626..2173621 + 996 WP_086057365.1 tripartite tricarboxylate transporter substrate binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10508.95 Da        Isoelectric Point: 6.3221

>T75997 WP_086057361.1 NZ_CP021110:2168854-2169132 [Bordetella genomosp. 9]
MLPIFWSAAALNDLAQITDYIAEYDVHAAIRLHALIENAVRPTSEHPYLYRPGRVPGTRELVAHPNYVVVYEVQGDRIEV
RAVLHARQEYPT

Download         Length: 279 bp

>T75997 NZ_CP021110:2168854-2169132 [Bordetella genomosp. 9]
ATGCTTCCTATTTTTTGGAGTGCCGCGGCACTCAATGATTTGGCCCAAATCACTGACTACATCGCGGAATACGACGTCCA
TGCGGCCATCCGGCTGCATGCGCTGATCGAAAATGCGGTGCGTCCAACGTCGGAACACCCCTATCTCTACCGCCCAGGAC
GTGTGCCGGGCACCCGCGAACTTGTCGCGCACCCGAACTACGTCGTGGTGTATGAAGTGCAGGGAGATCGGATCGAGGTC
AGAGCGGTCCTGCATGCGCGTCAGGAATACCCGACTTGA

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 7997.92 Da        Isoelectric Point: 7.0125

>AT75997 WP_086057360.1 NZ_CP021110:2168606-2168821 [Bordetella genomosp. 9]
MRAALSAIVSEFETAEQAASYDRWFRAKVQASRDDPRPSIPHDEAMARIREKLAAKLNGQQTAAIRPDDDR

Download         Length: 216 bp

>AT75997 NZ_CP021110:2168606-2168821 [Bordetella genomosp. 9]
ATGCGCGCAGCCCTTTCCGCAATCGTCTCGGAGTTCGAGACCGCTGAACAAGCGGCCAGCTATGACCGCTGGTTTCGCGC
CAAGGTACAAGCGAGCCGAGACGATCCTCGCCCCAGCATTCCGCATGATGAGGCAATGGCGCGCATCCGAGAAAAATTGG
CTGCGAAGCTGAACGGACAACAGACGGCCGCCATACGCCCTGACGATGACCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References