Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 441528..442101 Replicon chromosome
Accession NZ_CP021109
Organism Bordetella genomosp. 9 strain AU17164

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CAL13_RS02075 Protein ID WP_086071357.1
Coordinates 441528..441815 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CAL13_RS02080 Protein ID WP_086071358.1
Coordinates 441802..442101 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAL13_RS02050 437154..439184 - 2031 WP_086071353.1 DNA topoisomerase III -
CAL13_RS02055 439480..439863 - 384 WP_086071354.1 single-stranded DNA-binding protein -
CAL13_RS02060 439860..440408 - 549 WP_086071355.1 DUF3158 family protein -
CAL13_RS02065 440405..441184 - 780 WP_086071356.1 TIGR03761 family integrating conjugative element protein -
CAL13_RS02070 441308..441499 - 192 WP_027350501.1 hypothetical protein -
CAL13_RS02075 441528..441815 - 288 WP_086071357.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CAL13_RS02080 441802..442101 - 300 WP_086071358.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CAL13_RS02085 442229..443425 - 1197 WP_086071359.1 hypothetical protein -
CAL13_RS02090 443428..443988 - 561 WP_004255086.1 DUF2857 domain-containing protein -
CAL13_RS02095 444006..445664 - 1659 WP_086071360.1 ParB N-terminal domain-containing protein -
CAL13_RS02100 445657..445905 - 249 WP_048939778.1 hypothetical protein -
CAL13_RS02105 445889..446755 - 867 WP_086071361.1 ParA family protein -
CAL13_RS02110 446797..447015 - 219 WP_009461157.1 AlpA family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 331398..466043 134645


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-58)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10866.52 Da        Isoelectric Point: 9.8935

>T75993 WP_086071357.1 NZ_CP021109:c441815-441528 [Bordetella genomosp. 9]
VRVLEWRQAARADLLAIVDYISDDNPDAAQRLKNDIEAKAAKLPERPKLYRPGRVAGTREMVVRANYVVIYMEDTRAVSI
LRVLHAAQQWPPARE

Download         Length: 288 bp

>T75993 NZ_CP021109:c441815-441528 [Bordetella genomosp. 9]
GTGCGCGTACTTGAGTGGCGGCAAGCTGCCCGCGCCGACCTGCTGGCGATTGTTGACTACATCTCGGACGACAACCCCGA
TGCCGCGCAGCGGTTGAAGAACGACATCGAGGCCAAGGCCGCAAAGCTGCCGGAGCGCCCGAAGCTCTACCGGCCTGGCC
GCGTGGCCGGCACGCGGGAGATGGTCGTGCGTGCGAACTACGTGGTGATCTACATGGAGGACACCCGCGCGGTGTCCATC
CTGCGCGTGTTGCACGCCGCGCAGCAGTGGCCGCCGGCACGGGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10844.48 Da        Isoelectric Point: 8.6788

>AT75993 WP_086071358.1 NZ_CP021109:c442101-441802 [Bordetella genomosp. 9]
MAAQTSMLHIRVDDRLKADAAEKLAGVGLTVSDAVRILLTRVVKEGALPAGLTADPEAYDAWFRAKVQEALADTRPPVPH
QQVMDEAQALIDRKRRART

Download         Length: 300 bp

>AT75993 NZ_CP021109:c442101-441802 [Bordetella genomosp. 9]
ATGGCCGCACAGACTTCGATGCTGCACATCCGCGTGGACGACAGGCTCAAGGCCGATGCCGCCGAGAAGCTCGCCGGGGT
CGGCCTCACCGTTTCGGACGCCGTGCGCATCCTGCTGACCCGTGTGGTCAAGGAAGGTGCGCTGCCGGCTGGCCTCACGG
CCGACCCGGAGGCCTACGATGCCTGGTTCCGGGCAAAGGTCCAGGAGGCGCTGGCCGACACACGGCCGCCGGTGCCGCAC
CAGCAGGTCATGGACGAGGCGCAGGCCCTGATCGACAGGAAGCGGCGTGCGCGTACTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References