Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2578342..2579003 Replicon chromosome
Accession NZ_CP021107
Organism Bordetella genomosp. 6 strain AU22978

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CAL11_RS12070 Protein ID WP_086093071.1
Coordinates 2578578..2579003 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CAL11_RS12065 Protein ID WP_086093070.1
Coordinates 2578342..2578581 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAL11_RS12030 2573370..2574173 - 804 WP_086093065.1 bacteriocin family protein -
CAL11_RS12035 2574170..2575216 - 1047 WP_015063707.1 Dyp-type peroxidase -
CAL11_RS12040 2575294..2575854 - 561 WP_086093066.1 DUF488 domain-containing protein -
CAL11_RS12045 2575851..2576084 - 234 WP_033450420.1 DUF2945 domain-containing protein -
CAL11_RS12050 2576166..2576678 - 513 WP_086093067.1 redoxin domain-containing protein -
CAL11_RS12055 2576737..2577282 - 546 WP_086093068.1 peroxidase-related enzyme -
CAL11_RS12060 2577426..2578268 + 843 WP_086093069.1 AraC family transcriptional regulator -
CAL11_RS12065 2578342..2578581 + 240 WP_086093070.1 Arc family DNA-binding protein Antitoxin
CAL11_RS12070 2578578..2579003 + 426 WP_086093071.1 PIN domain-containing protein Toxin
CAL11_RS12075 2579113..2579577 + 465 WP_086093072.1 MarR family transcriptional regulator -
CAL11_RS12080 2579678..2581183 - 1506 WP_003812078.1 tripartite tricarboxylate transporter permease -
CAL11_RS12085 2581700..2582212 + 513 WP_086094571.1 hypothetical protein -
CAL11_RS12090 2582232..2583206 - 975 WP_086093073.1 tripartite tricarboxylate transporter substrate binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin

Arc-like DNA binding domain

(9-46)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 14848.11 Da        Isoelectric Point: 5.4757

>T75986 WP_086093071.1 NZ_CP021107:2578578-2579003 [Bordetella genomosp. 6]
MILLDTDVLLEPLRPAPDPAVAAWLDAQHVETLYLAALSVAEIQLGLARLPRGKRAETLRHEFERRILPLFMGHVLPFDA
AAADAYAAVMTQAAAAGHALDATDGCIAATATAHGLAIATRHPARFEAAGLAVVDPWQAAA

Download         Length: 426 bp

>T75986 NZ_CP021107:2578578-2579003 [Bordetella genomosp. 6]
ATGATCCTGCTCGATACCGACGTGCTGCTCGAACCGCTGCGGCCGGCCCCCGACCCGGCCGTCGCGGCATGGCTGGATGC
CCAGCACGTCGAGACCCTGTACCTGGCCGCGCTCAGCGTGGCCGAGATCCAGCTCGGGCTGGCCCGCCTGCCGCGCGGCA
AGCGGGCCGAGACGCTGCGCCACGAATTCGAGCGGCGCATCCTGCCCCTGTTCATGGGCCATGTCCTGCCTTTCGACGCG
GCCGCGGCCGACGCCTATGCCGCCGTCATGACGCAGGCCGCGGCGGCCGGCCACGCGCTGGACGCGACCGACGGCTGCAT
CGCCGCCACCGCCACCGCGCACGGCCTGGCCATCGCCACGCGCCATCCGGCCCGCTTCGAGGCGGCCGGGCTCGCCGTCG
TCGACCCATGGCAAGCCGCCGCTTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8565.77 Da        Isoelectric Point: 11.5658

>AT75986 WP_086093070.1 NZ_CP021107:2578342-2578581 [Bordetella genomosp. 6]
VSSITVRNVPEEVHRALRVRAATHGRSTEAEIRAILENAVLPDGRVKLGTLLSHIGRGTRGMDLTIERNPAPARAASFE

Download         Length: 240 bp

>AT75986 NZ_CP021107:2578342-2578581 [Bordetella genomosp. 6]
GTGTCTTCGATTACGGTAAGAAATGTTCCCGAGGAAGTGCATCGCGCCTTGCGCGTGCGCGCCGCCACGCATGGGCGCAG
CACCGAGGCCGAGATCCGCGCCATCCTGGAAAACGCCGTGCTGCCCGACGGGCGCGTCAAGCTGGGCACCCTGCTCAGCC
ACATCGGCCGCGGCACGCGCGGCATGGACCTGACCATCGAGCGCAACCCGGCGCCCGCCCGCGCGGCCAGCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References