Detailed information of TA system TA075951

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 6193941..6195058
• Replicon: chromosome
• Accession: NZ_CP021070
• Organism: Mesorhizobium sp. WSM1497

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: A9K65_RS30330
• Protein ID: WP_176479563.1
• Coordinates: 6194540..6195058 (+)
• Length: 173 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: A9K65_RS30325
• Protein ID: WP_084015684.1
• Coordinates: 6193941..6194540 (+)
• Length: 200 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A9K65_RS30320	6189778..6193836	-	4059	WP_064993355.1	helix-turn-helix domain-containing protein	-
A9K65_RS30325	6193941..6194540	+	600	WP_084015684.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
A9K65_RS30330	6194540..6195058	+	519	WP_176479563.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
A9K65_RS30335	6194961..6195675	+	715	Protein_5895	porin	-
A9K65_RS30340	6196649..6197401	+	753	WP_064993307.1	carbonic anhydrase	-
A9K65_RS30345	6197569..6200004	+	2436	WP_064993308.1	sensor histidine kinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	6189778..6248607	58829

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (38-152)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (9-50)

Sequences

Toxin

Protein

• Length: 173 a.a.
• Molecular weight: 19916.89 Da
• Isoelectric Point: 9.1310

>T75951 WP_176479563.1 NZ_CP021070:6194540-6195058 [Mesorhizobium sp. WSM1497]
MAKVLKNPAASIRDRLLQHSRQQGDDYQRILTRYAIERLLFRLSMTEASERYVLKGAMLFVTWPEYVFRPTGDLDLLGQG
DPDPGAIHDLFTRICQVEAPDEGIVFDAASLTVDPVREGKYQGVRLNLKGWPNSLQQRRQVDFRLDPAWWPACREGRLGL
RHVCRILRERLQ

Nucleotide

• Length: 519 bp

>T75951 NZ_CP021070:6194540-6195058 [Mesorhizobium sp. WSM1497]
ATGGCTAAGGTTCTCAAGAATCCTGCCGCCTCAATAAGAGACCGCCTTCTTCAGCACTCTAGGCAACAGGGTGACGACTA
TCAGCGCATCCTGACGCGGTATGCGATCGAACGCTTGCTTTTCCGCCTCAGTATGACCGAAGCGTCCGAGCGCTATGTAC
TCAAGGGCGCAATGCTGTTCGTGACCTGGCCCGAATACGTCTTCAGGCCAACCGGCGATCTTGACCTGCTCGGCCAAGGC
GACCCTGACCCCGGCGCCATTCACGACCTCTTCACCCGGATTTGCCAGGTCGAAGCTCCCGACGAAGGCATCGTCTTCGA
TGCGGCCTCCCTGACAGTCGATCCCGTGCGCGAAGGAAAATACCAAGGCGTTCGCCTGAACCTGAAGGGTTGGCCGAACA
GCCTTCAACAGCGGCGCCAAGTTGACTTCCGCCTGGATCCAGCTTGGTGGCCTGCGTGTCGGGAAGGACGACTCGGCCTT
CGACACGTTTGCCGGATACTCCGGGAACGTCTTCAATAA

Antitoxin

Protein

• Length: 200 a.a.
• Molecular weight: 22287.80 Da
• Isoelectric Point: 9.7609

>AT75951 WP_084015684.1 NZ_CP021070:6193941-6194540 [Mesorhizobium sp. WSM1497]
MTHRETALNLVRDRGIVRARDFTAAGIPLVYLRRLTEAGDIVRLRRGLYQHPERMGEDTDHDLAEAARIVPNGVVSLISA
LRHHGLTTQLPHAVWMTIPHKARTPHTPGLRLEIVRATCEVLASGVEFIRVEGVDVAIYGVAKTVADCFKHRRHVGEDVA
VEALRDALQQRKTIASELMKYAVIDRVTARIEPYIKAVQ

Nucleotide

• Length: 600 bp

>AT75951 NZ_CP021070:6193941-6194540 [Mesorhizobium sp. WSM1497]
ATGACCCACCGTGAGACCGCCCTGAATCTCGTTCGAGATCGCGGCATCGTGCGTGCGCGCGACTTTACGGCGGCCGGCAT
CCCGCTGGTCTATCTCAGGCGCCTTACCGAGGCCGGTGATATCGTACGTCTCAGGCGCGGTCTATACCAGCATCCCGAGC
GAATGGGCGAAGACACCGATCATGATCTGGCAGAAGCGGCACGTATTGTGCCGAACGGCGTGGTCAGCCTCATCAGCGCG
CTTCGTCACCACGGTTTGACGACCCAGCTTCCGCACGCGGTGTGGATGACGATACCACACAAGGCAAGGACGCCGCACAC
TCCAGGCCTGCGTCTGGAGATTGTTCGGGCGACCTGCGAAGTCCTGGCATCCGGAGTCGAGTTCATCCGCGTCGAAGGCG
TCGATGTAGCGATCTATGGCGTCGCAAAAACGGTTGCCGATTGCTTCAAGCATCGCCGTCATGTTGGCGAAGACGTCGCA
GTCGAGGCGCTCCGCGACGCTCTGCAACAACGAAAGACCATAGCGAGTGAGCTGATGAAGTACGCGGTCATTGATCGAGT
GACCGCCCGGATCGAGCCCTATATCAAGGCCGTACAATGA