Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 2783895..2784465 Replicon chromosome
Accession NZ_CP021056
Organism Richelia sinica FACHB-800 strain FACHB 800

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag B6N60_RS11760 Protein ID WP_190606892.1
Coordinates 2784166..2784465 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag B6N60_RS11755 Protein ID WP_190606890.1
Coordinates 2783895..2784185 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B6N60_RS11740 (B6N60_02602) 2779872..2781176 - 1305 WP_190606885.1 SPFH domain-containing protein -
B6N60_RS11745 (B6N60_02603) 2782198..2782563 + 366 WP_190606887.1 colicin E3/pyocin S6 family cytotoxin -
B6N60_RS11750 (B6N60_02604) 2783026..2783775 + 750 WP_190606888.1 DUF5677 domain-containing protein -
B6N60_RS11755 (B6N60_02605) 2783895..2784185 + 291 WP_190606890.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
B6N60_RS11760 (B6N60_02606) 2784166..2784465 + 300 WP_190606892.1 Txe/YoeB family addiction module toxin Toxin
B6N60_RS11765 (B6N60_02607) 2784551..2785405 - 855 WP_190606894.1 sulfite exporter TauE/SafE family protein -
B6N60_RS11770 (B6N60_02608) 2785402..2785947 - 546 WP_190606896.1 rhodanese-like domain-containing protein -
B6N60_RS11775 (B6N60_02609) 2786002..2786691 - 690 WP_190606898.1 MBL fold metallo-hydrolase -
B6N60_RS11780 (B6N60_02610) 2787064..2787765 + 702 WP_190606902.1 4Fe-4S dicluster domain-containing protein -
B6N60_RS11785 (B6N60_02611) 2787920..2788966 + 1047 WP_190606904.1 heterodisulfide reductase-related iron-sulfur binding cluster -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(20-99)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(5-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11937.62 Da        Isoelectric Point: 7.3170

>T75925 WP_190606892.1 NZ_CP021056:2784166-2784465 [Richelia sinica FACHB-800]
MTQKKNEPKPQEIKVRDAVFHPEFREDLVYWVETNRKTALRAFDLIEAIMRDPFTGVGKPEPLKYLDSDAWSRRLTQEHR
IVYLISDDRIDFLQARFHY

Download         Length: 300 bp

>T75925 NZ_CP021056:2784166-2784465 [Richelia sinica FACHB-800]
TTGACACAGAAGAAGAATGAACCCAAACCCCAAGAAATTAAAGTTCGGGATGCTGTCTTTCATCCAGAATTTAGGGAAGA
CCTTGTTTATTGGGTGGAGACAAACCGTAAAACTGCGCTCCGTGCTTTTGATTTAATTGAAGCAATTATGCGAGATCCTT
TTACTGGTGTTGGTAAACCAGAACCTCTGAAATATTTAGATTCAGATGCGTGGTCACGAAGACTTACTCAAGAACATCGA
ATTGTTTATCTAATTAGTGATGACAGAATTGATTTCTTACAAGCTAGATTTCATTATTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10681.97 Da        Isoelectric Point: 4.2182

>AT75925 WP_190606890.1 NZ_CP021056:2783895-2784185 [Richelia sinica FACHB-800]
MSNQTNLTDARNNLADICAQVVADREIMIITRPEGENVALIAADELESLLETTHLLRSPNNAARLLTALERAKTRTLNPQ
SINELRQELGIDTEEE

Download         Length: 291 bp

>AT75925 NZ_CP021056:2783895-2784185 [Richelia sinica FACHB-800]
ATGTCCAACCAAACAAACTTAACCGATGCTCGTAATAACCTAGCTGACATCTGCGCTCAAGTAGTTGCAGATAGAGAAAT
AATGATTATTACCCGACCAGAAGGTGAAAATGTCGCCTTAATTGCTGCTGACGAATTAGAAAGTTTATTAGAAACCACTC
ATTTACTACGCTCACCAAACAATGCAGCGCGTCTTTTAACAGCTTTAGAAAGAGCAAAAACTAGAACTTTAAATCCCCAA
AGTATCAACGAACTACGTCAGGAGTTGGGAATTGACACAGAAGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References