Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 3251271..3251806 Replicon chromosome
Accession NZ_CP021054
Organism Methylorubrum zatmanii strain PSBB041

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag B2G69_RS15220 Protein ID WP_085857037.1
Coordinates 3251516..3251806 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag B2G69_RS15215 Protein ID WP_056507176.1
Coordinates 3251271..3251519 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B2G69_RS15200 3246489..3248072 - 1584 WP_056507185.1 hypothetical protein -
B2G69_RS15205 3248072..3249439 - 1368 WP_056507183.1 SWIM zinc finger family protein -
B2G69_RS15210 3249635..3251137 - 1503 WP_056507180.1 glucose-6-phosphate dehydrogenase -
B2G69_RS15215 3251271..3251519 + 249 WP_056507176.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
B2G69_RS15220 3251516..3251806 + 291 WP_085857037.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
B2G69_RS15225 3251888..3252526 + 639 WP_056507477.1 uracil-DNA glycosylase family protein -
B2G69_RS15230 3252534..3254060 - 1527 WP_056507170.1 alginate export family protein -
B2G69_RS15235 3254385..3255083 + 699 WP_056507166.1 orotidine-5'-phosphate decarboxylase -
B2G69_RS15240 3255086..3255430 + 345 WP_003605408.1 DUF1330 domain-containing protein -
B2G69_RS15245 3255450..3256073 - 624 WP_012253132.1 TetR/AcrR family transcriptional regulator -
B2G69_RS15250 3256296..3256496 - 201 WP_003605412.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11059.61 Da        Isoelectric Point: 10.5105

>T75922 WP_085857037.1 NZ_CP021054:3251516-3251806 [Methylorubrum zatmanii]
MSVRFSPRARADLSRIWDDSAERWGADQADRYIRLLAGGFDRLAEDPARGLRADEIRKGYFRLSVGSHVLFYRLGAEGGI
EVIRILHGRMDFKRHL

Download         Length: 291 bp

>T75922 NZ_CP021054:3251516-3251806 [Methylorubrum zatmanii]
ATGAGCGTCCGCTTCTCGCCGAGGGCGCGCGCGGATCTCAGCCGGATCTGGGACGATTCGGCCGAGCGCTGGGGAGCGGA
TCAGGCCGACCGCTACATCCGCCTTCTGGCTGGAGGCTTCGACCGATTGGCGGAGGATCCGGCTCGGGGTCTAAGGGCCG
ACGAGATCCGCAAGGGGTATTTCCGCCTCTCTGTCGGATCGCACGTCCTATTCTACCGCCTGGGCGCCGAGGGCGGCATC
GAGGTCATCCGCATCCTTCATGGGCGGATGGATTTCAAACGCCATCTTTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9034.99 Da        Isoelectric Point: 4.5292

>AT75922 WP_056507176.1 NZ_CP021054:3251271-3251519 [Methylorubrum zatmanii]
MPRNTSVSLGEHFAQFIDRQVEGGRYGSASEVVRAGLRLLEEQEAALNTLRAALIEGEESGSPEPFDTETFLREKREGAI
RG

Download         Length: 249 bp

>AT75922 NZ_CP021054:3251271-3251519 [Methylorubrum zatmanii]
ATGCCGCGAAACACGTCCGTCTCGCTCGGCGAGCACTTTGCGCAGTTCATCGACCGCCAGGTCGAGGGGGGACGTTACGG
CTCCGCCAGCGAAGTGGTCCGGGCCGGGCTTCGTCTCCTTGAGGAGCAGGAGGCCGCCCTCAACACGCTCCGGGCCGCGC
TGATCGAGGGGGAGGAAAGCGGCTCGCCCGAGCCCTTCGATACGGAGACCTTTCTCCGGGAAAAGCGTGAGGGCGCGATC
CGAGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References