Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 686943..687523 Replicon plasmid pRspNXC14c
Accession NZ_CP021033
Organism Rhizobium sp. NXC14

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NXC14_RS31220 Protein ID WP_085781851.1
Coordinates 687140..687523 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NXC14_RS31215 Protein ID WP_085781850.1
Coordinates 686943..687143 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC14_RS31195 682784..683410 + 627 WP_085781846.1 response regulator transcription factor -
NXC14_RS31200 683684..683899 + 216 WP_085781847.1 hypothetical protein -
NXC14_RS31205 684465..685550 - 1086 WP_085781848.1 aldo/keto reductase -
NXC14_RS31210 685648..686577 + 930 WP_085781849.1 LysR family transcriptional regulator -
NXC14_RS31215 686943..687143 + 201 WP_085781850.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NXC14_RS31220 687140..687523 + 384 WP_085781851.1 type II toxin-antitoxin system VapC family toxin Toxin
NXC14_RS31225 687818..688024 - 207 WP_085781852.1 hypothetical protein -
NXC14_RS31230 688008..689078 - 1071 WP_085781853.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
NXC14_RS31235 689075..689797 - 723 WP_085781854.1 SDR family NAD(P)-dependent oxidoreductase -
NXC14_RS31240 689883..690317 + 435 WP_085781855.1 redox-sensitive transcriptional activator SoxR -
NXC14_RS31245 690910..691803 - 894 WP_085781856.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..889015 889015


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-113)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14240.41 Da        Isoelectric Point: 7.5611

>T75918 WP_085781851.1 NZ_CP021033:687140-687523 [Rhizobium sp. NXC14]
VILADTSVWIDHFRQVDAELRTIIEHDRLLCHPAVVGELALGSLRDRERVITFLAAQRQAFVATHDEVMTMIDRHGIFSM
GIGYTDAHLLASILLDRRAALWTKDKRLQAAAEKAGASLHKPAHPRN

Download         Length: 384 bp

>T75918 NZ_CP021033:687140-687523 [Rhizobium sp. NXC14]
GTGATACTGGCAGACACTTCTGTATGGATCGATCATTTTCGCCAAGTTGATGCGGAGCTTAGGACGATCATTGAGCACGA
TCGTCTACTCTGCCATCCGGCTGTGGTCGGCGAACTGGCACTTGGCAGCCTTCGAGATCGCGAGCGTGTGATTACATTTC
TGGCAGCCCAGCGCCAAGCGTTCGTCGCAACGCACGACGAAGTGATGACAATGATCGACCGTCACGGCATCTTCAGTATG
GGCATCGGCTATACCGATGCCCACTTGCTCGCCTCGATACTGCTTGATCGGCGAGCGGCATTATGGACCAAGGACAAGCG
TCTGCAGGCGGCGGCCGAAAAGGCAGGCGCTTCATTGCATAAGCCCGCCCATCCCCGCAACTAA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7110.24 Da        Isoelectric Point: 11.1107

>AT75918 WP_085781850.1 NZ_CP021033:686943-687143 [Rhizobium sp. NXC14]
MRSTINLDDTLMERAKSLTGTKETAALVRQALETLIRVESGKRLIALGGTMPDAEAAPRRRSAAAK

Download         Length: 201 bp

>AT75918 NZ_CP021033:686943-687143 [Rhizobium sp. NXC14]
ATGCGATCGACTATCAATCTCGACGATACTCTTATGGAAAGAGCCAAGTCCCTGACCGGCACAAAAGAAACCGCGGCTCT
CGTCCGCCAGGCGTTGGAGACGCTTATCCGAGTAGAGTCCGGAAAACGCCTGATCGCGCTCGGTGGAACTATGCCCGATG
CGGAGGCGGCTCCACGTCGCCGGAGCGCGGCGGCCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References