Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 510660..511195 Replicon plasmid pRspNXC14c
Accession NZ_CP021033
Organism Rhizobium sp. NXC14

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NXC14_RS30410 Protein ID WP_085782063.1
Coordinates 510660..510935 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NXC14_RS30415 Protein ID WP_085782064.1
Coordinates 510935..511195 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC14_RS30390 505864..506790 - 927 WP_085782062.1 sugar ABC transporter permease -
NXC14_RS30395 506843..508066 - 1224 WP_085781721.1 sugar ABC transporter substrate-binding protein -
NXC14_RS30400 508116..509435 - 1320 WP_085781722.1 alpha-L-fucosidase -
NXC14_RS30405 509646..510653 + 1008 WP_085781723.1 LacI family transcriptional regulator -
NXC14_RS30410 510660..510935 - 276 WP_085782063.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NXC14_RS30415 510935..511195 - 261 WP_085782064.1 ribbon-helix-helix domain-containing protein Antitoxin
NXC14_RS33230 511315..511503 - 189 WP_198175580.1 hypothetical protein -
NXC14_RS30420 511726..512739 + 1014 WP_085781724.1 ABC transporter substrate-binding protein -
NXC14_RS30425 512836..513654 + 819 WP_085781725.1 ABC transporter ATP-binding protein -
NXC14_RS30430 513666..514547 + 882 WP_085781726.1 ABC transporter permease -
NXC14_RS30435 514624..516021 - 1398 WP_085781727.1 sensor histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..889015 889015


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10770.35 Da        Isoelectric Point: 9.6906

>T75917 WP_085782063.1 NZ_CP021033:c510935-510660 [Rhizobium sp. NXC14]
IEVKWTSKAVSDIVRLNDFLSPVDRRPAARTVQALTAAPARLLEQPRLGERLEEFDPREVRRILVGRYELPYEIQQSTIY
VLRLWHTREDR

Download         Length: 276 bp

>T75917 NZ_CP021033:c510935-510660 [Rhizobium sp. NXC14]
ATCGAAGTCAAGTGGACGAGCAAAGCGGTCTCGGACATCGTCCGCTTAAACGACTTTCTCTCCCCGGTCGACCGACGCCC
CGCGGCCCGAACTGTACAGGCACTGACGGCAGCCCCCGCACGGCTGCTCGAACAGCCGCGTCTCGGCGAACGGCTTGAGG
AGTTCGATCCTCGTGAGGTCCGCCGCATTCTCGTTGGCCGTTATGAGCTACCCTACGAAATCCAGCAGTCGACGATCTAC
GTATTGCGGCTTTGGCATACGCGTGAGGATCGGTAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9701.97 Da        Isoelectric Point: 5.0623

>AT75917 WP_085782064.1 NZ_CP021033:c511195-510935 [Rhizobium sp. NXC14]
VETKVLTAHVPLPLAQKVDQLASRLERSRGWIVKQALTAWIDQEEERRRLTLEALADVNSGKVVDHQSVQAWADSLDTDA
PISFPW

Download         Length: 261 bp

>AT75917 NZ_CP021033:c511195-510935 [Rhizobium sp. NXC14]
GTGGAGACTAAAGTTCTGACGGCCCATGTTCCATTGCCGCTTGCGCAGAAGGTCGATCAGCTCGCATCTCGGCTCGAACG
TTCGCGGGGCTGGATCGTCAAGCAGGCCCTGACTGCATGGATTGACCAGGAAGAGGAGCGCCGGCGTTTGACGCTTGAGG
CGTTGGCCGACGTGAATAGCGGCAAAGTTGTCGATCACCAGTCTGTTCAAGCCTGGGCCGATAGTCTCGATACCGACGCG
CCGATTTCATTCCCCTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References