Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 11397..12064 Replicon plasmid pRspNXC14c
Accession NZ_CP021033
Organism Rhizobium sp. NXC14

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NXC14_RS28025 Protein ID WP_085781306.1
Coordinates 11397..11807 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NXC14_RS28030 Protein ID WP_085781307.1
Coordinates 11804..12064 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC14_RS28010 6790..7704 - 915 WP_085781304.1 hydrogen peroxide-inducible genes activator -
NXC14_RS28015 7848..10034 + 2187 WP_085782023.1 catalase/peroxidase HPI -
NXC14_RS28020 10576..11301 + 726 WP_085781305.1 SDR family oxidoreductase -
NXC14_RS28025 11397..11807 - 411 WP_085781306.1 type II toxin-antitoxin system VapC family toxin Toxin
NXC14_RS28030 11804..12064 - 261 WP_085781307.1 antitoxin Antitoxin
NXC14_RS28035 12140..12697 - 558 WP_085781308.1 DUF3299 domain-containing protein -
NXC14_RS28045 12967..13539 - 573 WP_085781309.1 pyridoxamine 5'-phosphate oxidase family protein -
NXC14_RS28050 13550..14254 - 705 WP_085781310.1 SDR family oxidoreductase -
NXC14_RS28055 14361..15236 + 876 WP_085782024.1 LysR family transcriptional regulator -
NXC14_RS28060 15308..16276 - 969 WP_085782025.1 zinc-dependent alcohol dehydrogenase family protein -
NXC14_RS28065 16330..16746 + 417 WP_085781311.1 acyl-CoA thioesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..889015 889015


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-126)

Antitoxin

SpoVT-AbrB domain

(8-45)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 14911.15 Da        Isoelectric Point: 5.1787

>T75916 WP_085781306.1 NZ_CP021033:c11807-11397 [Rhizobium sp. NXC14]
VITHLIDTNAVIALIGRKSDMLLAHVMDSDEGSIGLSSIVMHELYYGAYKSAKISYNLETLRLFMADFPTVGFEREDALA
AGEIRAALAAKGTPIGPYDVLLAAQAKTRDLVLITNNVGEFRRVDGLRVEDWTTVR

Download         Length: 411 bp

>T75916 NZ_CP021033:c11807-11397 [Rhizobium sp. NXC14]
GTGATCACTCATCTCATCGATACCAATGCGGTTATCGCTCTGATCGGCCGGAAGTCCGACATGCTGCTCGCCCACGTCAT
GGACAGCGACGAGGGATCGATCGGGCTGTCGAGCATCGTCATGCACGAGCTCTATTACGGCGCCTACAAGAGCGCGAAAA
TTTCCTACAATCTCGAAACCCTGCGCCTGTTCATGGCGGATTTCCCGACCGTCGGTTTCGAGCGCGAGGATGCGCTGGCC
GCTGGAGAGATCCGCGCGGCGTTGGCGGCAAAGGGAACACCGATCGGTCCTTATGATGTGCTGTTAGCCGCGCAGGCGAA
GACGCGGGACCTTGTTCTTATTACGAACAACGTCGGGGAGTTCCGGCGCGTGGATGGCCTGCGCGTCGAGGATTGGACGA
CCGTGCGGTAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9908.98 Da        Isoelectric Point: 4.8605

>AT75916 WP_085781307.1 NZ_CP021033:c12064-11804 [Rhizobium sp. NXC14]
MPQYARVFQSGNSQAVRLPKEFRFDVDQVEVTREGDAIILRPRTDHGGRWASLRSALERGLSDDFMAEGREQPEDQERTG
LQDLFK

Download         Length: 261 bp

>AT75916 NZ_CP021033:c12064-11804 [Rhizobium sp. NXC14]
ATGCCGCAATATGCGCGCGTCTTTCAATCCGGCAATTCGCAGGCCGTCCGGCTGCCGAAGGAGTTTCGCTTCGACGTCGA
TCAGGTGGAAGTGACACGGGAAGGCGATGCGATCATTCTGCGGCCGCGGACCGATCACGGCGGCCGCTGGGCCTCGTTGC
GCAGCGCCCTGGAGCGCGGCCTCAGCGACGATTTCATGGCGGAGGGACGTGAGCAGCCAGAAGATCAGGAGAGAACTGGC
CTTCAGGACTTGTTCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References