Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-RHH
Location 339278..339852 Replicon plasmid pRspNXC14b
Accession NZ_CP021032
Organism Rhizobium sp. NXC14

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NXC14_RS25930 Protein ID WP_085780891.1
Coordinates 339487..339852 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NXC14_RS25925 Protein ID WP_085781264.1
Coordinates 339278..339493 (+) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC14_RS25905 334606..335592 - 987 WP_085780888.1 UbiA prenyltransferase family protein -
NXC14_RS25910 335830..337326 - 1497 Protein_308 ISL3 family transposase -
NXC14_RS25915 337836..338756 + 921 WP_085780889.1 DUF1738 domain-containing protein -
NXC14_RS25920 338842..339051 - 210 WP_085780890.1 hypothetical protein -
NXC14_RS25925 339278..339493 + 216 WP_085781264.1 ribbon-helix-helix domain-containing protein Antitoxin
NXC14_RS25930 339487..339852 + 366 WP_085780891.1 type II toxin-antitoxin system VapC family toxin Toxin
NXC14_RS25935 339949..340259 + 311 Protein_313 toprim domain-containing protein -
NXC14_RS25940 341041..341364 + 324 WP_085780892.1 DUF736 family protein -
NXC14_RS25945 341900..342205 - 306 WP_085780893.1 WGR domain-containing protein -
NXC14_RS33190 342204..342419 + 216 WP_085780894.1 hypothetical protein -
NXC14_RS25955 342416..342898 + 483 WP_085780895.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..773015 773015


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-106)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-40)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13538.90 Da        Isoelectric Point: 7.2028

>T75915 WP_085780891.1 NZ_CP021032:339487-339852 [Rhizobium sp. NXC14]
MVKSLFDTNVLIDYLNAVPQARGELARYREKAISIITWMEVLVGAKPEVAIGTRAFLAGFAVLAVDDAIAERAVSLRQLH
RIKLPDAIIWATANVHSMLLITRNTKDFPPELPEIRVPYEI

Download         Length: 366 bp

>T75915 NZ_CP021032:339487-339852 [Rhizobium sp. NXC14]
ATGGTAAAGTCTCTGTTCGACACCAATGTCTTAATCGACTATCTCAACGCAGTTCCGCAAGCGCGAGGCGAACTGGCAAG
ATATCGCGAGAAGGCGATTAGCATCATCACCTGGATGGAGGTTCTCGTCGGTGCCAAGCCTGAGGTTGCGATCGGAACGC
GCGCTTTCCTGGCGGGCTTTGCAGTCCTCGCTGTCGATGACGCCATAGCCGAACGAGCAGTATCTCTGCGACAACTTCAT
CGTATCAAGCTTCCCGATGCCATAATCTGGGCAACGGCCAATGTTCACTCGATGTTGCTGATTACACGAAACACAAAGGA
TTTCCCTCCCGAATTGCCCGAAATACGAGTGCCTTACGAAATCTGA

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8180.24 Da        Isoelectric Point: 4.7571

>AT75915 WP_085781264.1 NZ_CP021032:339278-339493 [Rhizobium sp. NXC14]
MRTLVDIGDPEVKALDRLAQREKMSRAALIRKAINDFLARNNADVEAEAFGLWGDRQIDGLTYQENMRSEW

Download         Length: 216 bp

>AT75915 NZ_CP021032:339278-339493 [Rhizobium sp. NXC14]
ATGAGAACGTTGGTGGATATCGGCGACCCAGAAGTCAAAGCGCTGGACCGGCTGGCACAGCGGGAAAAAATGTCTAGGGC
AGCGCTGATCCGAAAGGCGATCAATGACTTTCTGGCCAGGAACAATGCCGATGTTGAAGCAGAAGCGTTCGGCCTCTGGG
GCGATCGACAGATCGATGGCTTGACCTATCAGGAAAACATGCGCAGCGAATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References