Detailed information of TA system TA075914

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/CC2985(antitoxin)
• Location: 316144..316688
• Replicon: plasmid pRspNXC14b
• Accession: NZ_CP021032
• Organism: Rhizobium sp. NXC14

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: NXC14_RS25815
• Protein ID: WP_085780872.1
• Coordinates: 316398..316688 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: NXC14_RS25810
• Protein ID: WP_085780871.1
• Coordinates: 316144..316398 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NXC14_RS25795	312195..313208	+	1014	WP_085780868.1	alpha-ketoacid dehydrogenase subunit beta	-
NXC14_RS25800	313212..314456	+	1245	WP_085780869.1	2-oxo acid dehydrogenase subunit E2	-
NXC14_RS25805	314460..315857	+	1398	WP_085780870.1	dihydrolipoyl dehydrogenase	-
NXC14_RS25810	316144..316398	+	255	WP_085780871.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
NXC14_RS25815	316398..316688	+	291	WP_085780872.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
NXC14_RS25820	316965..317117	+	153	Protein_290	helix-turn-helix domain-containing protein	-
NXC14_RS25825	317324..318085	-	762	WP_085780873.1	slipin family protein	-
NXC14_RS25830	318115..319518	-	1404	WP_085780874.1	nodulation protein NfeD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Mobilizable plasmid	-	-	1..773015	773015

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-91)

Antitoxin

• Antitoxin ParD (3-66)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11009.54 Da
• Isoelectric Point: 5.1500

>T75914 WP_085780872.1 NZ_CP021032:316398-316688 [Rhizobium sp. NXC14]
MRFDLSVEAEEDIIAIAEQGVRMFGAAQARLYHDELFTALDLIAANPRMAREREEISPPVRVHPFKAHLIVYRIEDGTIF
VIRIRHGHEDWASDPA

Nucleotide

• Length: 291 bp

>T75914 NZ_CP021032:316398-316688 [Rhizobium sp. NXC14]
ATGCGCTTTGACCTTTCAGTCGAAGCGGAAGAGGACATCATTGCGATCGCCGAACAAGGAGTGCGCATGTTCGGAGCCGC
ACAGGCTAGGCTGTATCATGACGAGTTGTTTACCGCGCTTGATCTGATTGCGGCCAATCCCCGAATGGCGCGTGAGCGAG
AAGAGATTTCGCCGCCAGTTAGAGTTCATCCGTTCAAAGCCCATCTCATTGTCTACCGCATCGAGGACGGAACTATATTC
GTGATCCGAATACGCCATGGACACGAAGACTGGGCCAGCGATCCCGCTTAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9235.42 Da
• Isoelectric Point: 10.4462

>AT75914 WP_085780871.1 NZ_CP021032:316144-316398 [Rhizobium sp. NXC14]
MATMNVSLPDPMKDWVEAQAKSGRYSNASDYVRDLIRRDQIRGDKVAAMQRFVDDGLKSGIGSRSKGELFAAAVARAETT
RGSR

Nucleotide

• Length: 255 bp

>AT75914 NZ_CP021032:316144-316398 [Rhizobium sp. NXC14]
ATGGCTACGATGAACGTATCTCTTCCGGACCCGATGAAAGATTGGGTTGAGGCACAAGCAAAGAGCGGGCGATATTCCAA
TGCCAGTGACTATGTGCGCGACCTGATCCGGAGGGACCAAATTCGCGGTGACAAGGTTGCCGCCATGCAACGTTTCGTTG
ATGACGGTTTAAAAAGCGGTATTGGCAGCCGCTCGAAGGGCGAACTCTTTGCCGCCGCAGTGGCACGTGCAGAAACAACG
CGCGGCAGTAGATAA