Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 485014..485690 Replicon plasmid pRspNXC14a
Accession NZ_CP021031
Organism Rhizobium sp. NXC14

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NXC14_RS24095 Protein ID WP_085780546.1
Coordinates 485014..485436 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NXC14_RS24100 Protein ID WP_085780547.1
Coordinates 485433..485690 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NXC14_RS24070 480074..480967 + 894 WP_085780544.1 hypothetical protein -
NXC14_RS24075 481326..481583 - 258 WP_020923330.1 WGR domain-containing protein -
NXC14_RS24080 481956..482753 - 798 WP_085780545.1 3'(2'),5'-bisphosphate nucleotidase CysQ -
NXC14_RS24085 483950..484645 - 696 Protein_440 IS110 family transposase -
NXC14_RS32680 484644..484748 + 105 Protein_441 type IV secretory system conjugative DNA transfer family protein -
NXC14_RS24090 484749..484982 - 234 Protein_442 type IV secretory system conjugative DNA transfer family protein -
NXC14_RS24095 485014..485436 - 423 WP_085780546.1 type II toxin-antitoxin system VapC family toxin Toxin
NXC14_RS24100 485433..485690 - 258 WP_085780547.1 plasmid stability protein stbC Antitoxin
NXC14_RS32685 486397..486576 - 180 WP_157131492.1 DUF2384 domain-containing protein -
NXC14_RS24110 486782..487515 - 734 Protein_446 transposase -
NXC14_RS24115 487715..488749 - 1035 WP_085780612.1 cytochrome-c peroxidase -
NXC14_RS32690 489836..489991 + 156 WP_157131493.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..530065 530065
- flank IS/Tn - - 487285..487515 230


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15213.65 Da        Isoelectric Point: 4.8538

>T75912 WP_085780546.1 NZ_CP021031:c485436-485014 [Rhizobium sp. NXC14]
MIVIDTNVVSELWKAEPDRNVMAWIDAQMIETLYLSAITVAELRFGLAAMPAGKRRTIYLNRLEGEVLPALAGRILPFDL
DASRTYADLMAQAKRAGKAISNADGYIAATALARGFMVATRDTSPFAAAGLDIINPWEAL

Download         Length: 423 bp

>T75912 NZ_CP021031:c485436-485014 [Rhizobium sp. NXC14]
ATGATCGTCATCGATACCAACGTCGTTTCCGAACTGTGGAAGGCCGAGCCCGACCGCAATGTGATGGCCTGGATCGATGC
GCAGATGATCGAAACGCTGTATTTATCCGCAATTACGGTGGCCGAACTGCGTTTCGGCTTGGCGGCCATGCCAGCAGGCA
AGCGACGCACGATCTATCTGAATCGCTTGGAAGGAGAGGTATTGCCGGCCCTAGCGGGGCGCATACTCCCCTTCGACTTG
GATGCGTCACGAACTTATGCCGATCTGATGGCGCAAGCCAAGAGGGCAGGCAAAGCCATCAGCAATGCGGATGGCTATAT
CGCCGCAACGGCGTTGGCACGTGGGTTCATGGTCGCTACGCGCGATACCAGCCCATTCGCGGCCGCTGGGCTAGATATCA
TCAACCCCTGGGAGGCGCTATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9432.72 Da        Isoelectric Point: 6.2275

>AT75912 WP_085780547.1 NZ_CP021031:c485690-485433 [Rhizobium sp. NXC14]
MASVTVRNLPDEVHRALRVRAAMHGRSTEAEIREILETIVRPPERVKLGSLLASIARDAGGLTDAEAEHFNQLRDKTPAE
PMSFE

Download         Length: 258 bp

>AT75912 NZ_CP021031:c485690-485433 [Rhizobium sp. NXC14]
ATGGCGAGCGTGACCGTTAGGAACCTGCCGGATGAGGTGCACCGCGCGCTTCGCGTGAGAGCAGCGATGCATGGCCGCAG
CACCGAGGCCGAGATCCGCGAGATCCTCGAAACGATTGTCCGTCCGCCGGAGCGCGTCAAACTCGGTTCTTTATTGGCGT
CTATTGCCCGTGACGCAGGAGGGCTGACCGATGCTGAAGCGGAGCATTTCAACCAGCTGCGTGACAAGACACCGGCTGAA
CCGATGAGCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References