Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 343702..344399 Replicon plasmid pRetTAL182d
Accession NZ_CP021028
Organism Rhizobium sp. TAL182

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag Tal182_RS28235 Protein ID WP_085861625.1
Coordinates 343702..344148 (-) Length 149 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag Tal182_RS28240 Protein ID WP_064808528.1
Coordinates 344145..344399 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Tal182_RS28215 339501..340793 + 1293 WP_085861622.1 L-rhamnose catabolism isomerase -
Tal182_RS28220 340861..341319 - 459 WP_085861623.1 carboxymuconolactone decarboxylase family protein -
Tal182_RS28225 341428..342297 + 870 WP_085861624.1 sigma-70 family RNA polymerase sigma factor -
Tal182_RS28230 342469..343677 + 1209 WP_085861758.1 amidohydrolase/deacetylase family metallohydrolase -
Tal182_RS28235 343702..344148 - 447 WP_085861625.1 type II toxin-antitoxin system VapC family toxin Toxin
Tal182_RS28240 344145..344399 - 255 WP_064808528.1 hypothetical protein Antitoxin
Tal182_RS28245 344487..345326 - 840 WP_064808530.1 IclR family transcriptional regulator -
Tal182_RS28250 345480..345902 - 423 WP_085861626.1 type II toxin-antitoxin system VapC family toxin -
Tal182_RS28255 345902..346150 - 249 WP_085861627.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
Tal182_RS28260 346266..347123 + 858 WP_085861628.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..506213 506213


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 149 a.a.        Molecular weight: 15754.90 Da        Isoelectric Point: 4.8781

>T75910 WP_085861625.1 NZ_CP021028:c344148-343702 [Rhizobium sp. TAL182]
MIVLDTNVLSEAMKPAPNPAARSWLNEQVAETLYLSSVTLAELLFGIGTLPDGRRKAALSETLGGVLDLFGDRILPFDVG
AARHYADLAVRARADGKGFPTPNGYIAAIAASKGFMIATRDVSPFEAAGLIVINPWNHRSSEASQEDS

Download         Length: 447 bp

>T75910 NZ_CP021028:c344148-343702 [Rhizobium sp. TAL182]
ATGATCGTCCTGGATACGAACGTCCTTTCCGAGGCGATGAAACCGGCTCCCAATCCGGCAGCGCGTTCGTGGCTGAACGA
GCAGGTCGCTGAAACCTTGTATCTATCGAGTGTGACCTTGGCCGAACTGCTGTTTGGCATCGGTACGTTGCCGGACGGTC
GGCGCAAAGCGGCTCTGAGCGAAACGCTCGGCGGCGTGCTCGACCTGTTTGGCGATCGGATATTGCCGTTCGACGTCGGA
GCGGCCCGGCATTATGCCGACCTTGCCGTCAGAGCGCGAGCGGACGGCAAAGGCTTCCCAACTCCCAATGGATATATCGC
CGCCATTGCCGCTTCGAAGGGCTTTATGATCGCAACGCGCGACGTGAGCCCGTTTGAGGCGGCAGGACTGATTGTCATAA
ATCCCTGGAACCATCGATCATCCGAGGCCTCTCAGGAGGATTCATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9385.62 Da        Isoelectric Point: 5.1358

>AT75910 WP_064808528.1 NZ_CP021028:c344399-344145 [Rhizobium sp. TAL182]
MAVLTVRNVPDEVHRALRVRAAMHGRSTEAEVREILESAVKPEQRIRMGDALAALSRQQGLTDDDFAVFDQVRDSAPAEP
LKFE

Download         Length: 255 bp

>AT75910 NZ_CP021028:c344399-344145 [Rhizobium sp. TAL182]
ATGGCCGTTCTGACGGTTCGAAATGTGCCCGATGAAGTGCATCGGGCATTGCGCGTGCGGGCGGCCATGCACGGCCGCAG
CACCGAGGCGGAAGTTCGTGAAATCCTGGAAAGTGCGGTGAAGCCGGAGCAACGCATTCGCATGGGGGATGCCTTGGCGG
CGCTCAGTCGGCAGCAGGGGCTAACCGATGATGATTTCGCAGTGTTCGATCAGGTACGCGACAGCGCGCCGGCGGAGCCG
TTGAAGTTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References