Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 198409..199094 Replicon plasmid pRetTAL182b
Accession NZ_CP021026
Organism Rhizobium sp. TAL182

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag Tal182_RS23940 Protein ID WP_085861274.1
Coordinates 198672..199094 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag Tal182_RS23935 Protein ID WP_085861273.1
Coordinates 198409..198675 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Tal182_RS23915 194084..194773 + 690 WP_085861270.1 ABC transporter permease -
Tal182_RS23920 194851..195759 + 909 WP_085861271.1 homocysteine S-methyltransferase family protein -
Tal182_RS23925 195817..196251 - 435 WP_064811901.1 MarR family transcriptional regulator -
Tal182_RS23930 196458..198272 + 1815 WP_085861272.1 chloride channel protein -
Tal182_RS23935 198409..198675 + 267 WP_085861273.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
Tal182_RS23940 198672..199094 + 423 WP_085861274.1 type II toxin-antitoxin system VapC family toxin Toxin
Tal182_RS23945 199134..199904 - 771 WP_085861275.1 ABC transporter ATP-binding protein -
Tal182_RS23950 199914..200897 - 984 WP_085861276.1 ABC transporter substrate-binding protein -
Tal182_RS23955 200936..201787 - 852 WP_085861277.1 ABC transporter permease -
Tal182_RS23960 201798..203150 - 1353 WP_085861278.1 LLM class flavin-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..280614 280614


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-66)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15572.87 Da        Isoelectric Point: 6.2234

>T75907 WP_085861274.1 NZ_CP021026:198672-199094 [Rhizobium sp. TAL182]
VKLLLDTNVLSEVTKPNPDVRVLEWLGKLDEDHSFISIVSVAEIRRGVALMDKGRKRDALAEWLAHDLTQRFEHRIIPVD
EPVALAWGDLMGHAKRSGRGLSSMDGLIAATAIAHHFSLATRNIRDFEGFGIELIDPWAG

Download         Length: 423 bp

>T75907 NZ_CP021026:198672-199094 [Rhizobium sp. TAL182]
GTGAAGCTTTTGCTGGATACCAATGTCCTGTCCGAGGTGACCAAGCCGAACCCCGACGTGCGCGTCCTTGAATGGCTGGG
CAAGCTCGACGAGGATCATTCCTTCATCAGCATCGTGTCGGTAGCGGAGATCCGGCGCGGCGTTGCGCTGATGGACAAGG
GACGCAAACGCGACGCGCTCGCCGAATGGCTCGCCCACGACCTGACGCAACGCTTCGAGCATCGCATCATTCCGGTGGAT
GAACCGGTTGCCCTGGCCTGGGGAGACCTTATGGGCCATGCAAAACGGAGTGGCCGCGGCCTGTCGTCGATGGACGGCCT
GATCGCGGCGACAGCGATTGCTCATCATTTCAGCCTCGCGACGCGCAACATTAGGGATTTCGAGGGTTTTGGGATCGAAC
TGATCGATCCCTGGGCCGGGTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9768.02 Da        Isoelectric Point: 6.3426

>AT75907 WP_085861273.1 NZ_CP021026:198409-198675 [Rhizobium sp. TAL182]
MQPPPQADESWTVASAKAKLSEVIERAQSAPQTITRNGKPSVVVVSAEEWQRKTARKGTLAEFLMQSPLRGADLDLERQR
DEPRDPAL

Download         Length: 267 bp

>AT75907 NZ_CP021026:198409-198675 [Rhizobium sp. TAL182]
ATGCAGCCGCCACCGCAAGCCGATGAAAGCTGGACCGTTGCCAGCGCAAAGGCGAAGCTTTCCGAGGTCATCGAACGCGC
GCAATCCGCGCCGCAGACAATCACACGCAACGGCAAGCCCAGTGTCGTCGTCGTCTCTGCCGAGGAATGGCAGCGGAAGA
CCGCCCGCAAGGGAACGCTTGCCGAATTTCTGATGCAATCGCCCTTACGCGGCGCCGATCTGGACCTTGAACGTCAACGC
GATGAACCGCGTGATCCGGCGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References