Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 384848..385479 Replicon chromosome
Accession NZ_CP021024
Organism Rhizobium sp. TAL182

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag Tal182_RS01950 Protein ID WP_085857902.1
Coordinates 384848..385240 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag Tal182_RS01955 Protein ID WP_085857903.1
Coordinates 385237..385479 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Tal182_RS01930 380228..381436 - 1209 WP_064800408.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
Tal182_RS01935 381767..382531 - 765 WP_085857901.1 SDR family oxidoreductase -
Tal182_RS01940 382657..383583 + 927 WP_004673976.1 LysR family transcriptional regulator -
Tal182_RS01945 383588..384831 + 1244 Protein_374 MFS transporter -
Tal182_RS01950 384848..385240 - 393 WP_085857902.1 type II toxin-antitoxin system VapC family toxin Toxin
Tal182_RS01955 385237..385479 - 243 WP_085857903.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
Tal182_RS01960 385532..387193 - 1662 WP_085857904.1 urocanate hydratase -
Tal182_RS01965 387466..387795 - 330 WP_064800414.1 TfoX/Sxy family protein -
Tal182_RS01970 387799..388896 - 1098 WP_085857905.1 DUF917 family protein -
Tal182_RS01975 388877..390157 - 1281 WP_085857906.1 Zn-dependent hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

SpoVT-AbrB domain

(7-44)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14390.51 Da        Isoelectric Point: 6.4753

>T75905 WP_085857902.1 NZ_CP021024:c385240-384848 [Rhizobium sp. TAL182]
MTYLLDTNAVIALMKGNERLIAGLRRHRPQDFAIPAIVAHELFYGAYKSLRIEENLARIDGLQFAVLEFDRNDAQKAGEI
RAALQASGTPIGPYDVLIAGQAVARGLILITRNLREFERAAGLQAENWEG

Download         Length: 393 bp

>T75905 NZ_CP021024:c385240-384848 [Rhizobium sp. TAL182]
ATGACGTATCTCCTCGATACGAATGCCGTCATCGCCTTGATGAAGGGTAACGAGAGGCTGATCGCCGGACTGCGCAGACA
CAGGCCGCAGGATTTCGCCATCCCGGCAATCGTCGCGCACGAACTCTTCTACGGTGCTTACAAAAGCCTCCGCATCGAAG
AGAATCTGGCACGGATCGACGGGCTGCAATTCGCCGTCCTGGAATTCGACCGGAACGATGCGCAAAAGGCGGGGGAAATC
CGGGCTGCACTGCAAGCGTCGGGAACGCCGATTGGACCTTATGACGTGCTGATTGCCGGGCAGGCCGTCGCCCGCGGCCT
CATTCTGATTACCCGCAACCTCAGGGAGTTCGAACGCGCGGCAGGTTTGCAGGCCGAGAATTGGGAAGGCTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9131.25 Da        Isoelectric Point: 4.2463

>AT75905 WP_085857903.1 NZ_CP021024:c385479-385237 [Rhizobium sp. TAL182]
METAKIFWSGRSQAVRLPKEFRFDGDSVAIRRQGRAIILEPISDDWEWLADVIGPVDPDFAAAAEEQPAPQERPELDFFK

Download         Length: 243 bp

>AT75905 NZ_CP021024:c385479-385237 [Rhizobium sp. TAL182]
ATGGAAACAGCAAAGATTTTCTGGTCGGGACGTTCCCAAGCCGTCCGGCTGCCCAAGGAATTTCGTTTCGATGGTGACAG
TGTCGCCATTCGGCGGCAGGGGCGTGCGATCATTCTTGAGCCGATTTCCGACGATTGGGAGTGGCTAGCCGACGTGATCG
GTCCTGTCGATCCCGACTTTGCAGCGGCAGCGGAAGAGCAGCCCGCCCCGCAAGAGCGACCCGAGCTCGACTTCTTCAAA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References