Detailed information of TA system TA075904

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 2501452..2502998
• Replicon: chromosome
• Accession: NZ_CP021023
• Organism: Sedimentisphaera salicampi strain ST-PulAB-D4

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: STSP1_RS09500
• Protein ID: WP_085756111.1
• Coordinates: 2502057..2502998 (+)
• Length: 314 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: STSP1_RS09495
• Protein ID: WP_085756110.1
• Coordinates: 2501452..2502060 (+)
• Length: 203 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
STSP1_RS09475	2497511..2498932	-	1422	WP_085756106.1	sigma 54-interacting transcriptional regulator	-
STSP1_RS09480	2499321..2499605	+	285	WP_085756107.1	hypothetical protein	-
STSP1_RS09485	2499697..2500458	+	762	WP_085756108.1	DUF3800 domain-containing protein	-
STSP1_RS09490	2500618..2501142	+	525	WP_123807028.1	hypothetical protein	-
STSP1_RS09495	2501452..2502060	+	609	WP_085756110.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
STSP1_RS09500	2502057..2502998	+	942	WP_085756111.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
STSP1_RS09510	2503553..2504671	+	1119	WP_123807029.1	hypothetical protein	-
STSP1_RS09515	2504716..2504934	+	219	WP_085756114.1	hypothetical protein	-
STSP1_RS09520	2504952..2506286	-	1335	WP_085756115.1	DNA recombination protein RmuC	-
STSP1_RS09525	2506481..2507899	-	1419	WP_085756116.1	sulfatase-like hydrolase/transferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (39-266)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (7-53)

Sequences

Toxin

Protein

• Length: 314 a.a.
• Molecular weight: 36032.17 Da
• Isoelectric Point: 8.8728

>T75904 WP_085756111.1 NZ_CP021023:2502057-2502998 [Sedimentisphaera salicampi]
MSNREKKNIADSILQRLKNYSQMQREDRGLTLTNYAIERFLYRLSNSQYAGQFVLKGAQLFRVWGNNPYRPTRDLDLLGF
GNPDVSQLEEVFRNICRVETDVQDGIIYKAESVRGQAIREDNMYDGVRIKLEYRIGRTGEFMQVDIGFGDAVDSSAKMVA
FPSILNMPAPELRVYPYELAVAEKVEAMAALGFANSRMKDFYDVYQLAGEFEFDGKLLAQAIQTTFKRRGTVIPEGLPTA
FTKEFCEDKLKQRQWEAFISKNSLKEISFPSAADKIKDFILPVLRALAESKSFELIWKPGRQWSKERKNWSNC

Nucleotide

• Length: 942 bp

>T75904 NZ_CP021023:2502057-2502998 [Sedimentisphaera salicampi]
ATGAGCAATCGGGAAAAGAAAAACATAGCTGATTCCATTTTACAGCGTCTGAAAAATTATTCGCAGATGCAAAGGGAAGA
TCGCGGCCTTACGCTAACAAATTATGCAATAGAGCGTTTTCTTTATCGATTGAGCAATTCTCAATATGCCGGTCAGTTTG
TTCTCAAGGGAGCGCAGCTTTTTCGGGTATGGGGGAATAATCCTTACCGGCCAACGAGAGATCTTGATTTGCTTGGGTTC
GGCAATCCTGATGTTTCCCAGCTGGAGGAGGTTTTCAGAAATATTTGCCGGGTCGAAACTGATGTGCAGGACGGCATCAT
ATATAAAGCGGAATCTGTGAGAGGGCAGGCAATTCGGGAAGATAATATGTATGACGGCGTAAGGATTAAGCTTGAATACA
GAATAGGGCGTACGGGAGAATTTATGCAGGTAGATATTGGGTTTGGAGATGCGGTTGATTCTTCTGCAAAGATGGTTGCT
TTCCCCTCAATCCTGAATATGCCTGCCCCCGAGCTCAGGGTGTATCCATATGAACTGGCAGTGGCGGAAAAGGTTGAAGC
AATGGCAGCTCTTGGTTTTGCAAACAGTCGGATGAAAGACTTTTACGATGTGTATCAGCTTGCGGGAGAATTTGAATTCG
ACGGCAAACTCTTAGCTCAGGCGATTCAAACTACATTCAAGCGAAGGGGGACAGTGATACCAGAAGGGCTTCCCACTGCG
TTTACCAAAGAATTCTGCGAGGACAAATTGAAACAGAGGCAGTGGGAAGCTTTTATCTCAAAAAATAGCCTAAAAGAGAT
TTCTTTTCCATCAGCAGCAGACAAAATAAAAGATTTTATTCTTCCGGTGCTCAGAGCTTTGGCAGAAAGTAAAAGCTTTG
AACTTATTTGGAAACCCGGCAGACAATGGAGTAAAGAAAGAAAAAATTGGAGCAACTGTTAA

Antitoxin

Protein

• Length: 203 a.a.
• Molecular weight: 23330.18 Da
• Isoelectric Point: 10.3076

>AT75904 WP_085756110.1 NZ_CP021023:2501452-2502060 [Sedimentisphaera salicampi]
MGIKAQKLIENLRQYGMLKTGEIVELGISKEYLRKLTVQGTVERVSRGLYTLPNNDYSPMQSIAEVSKQVPKGVICLLSA
LRFHGFTTQNPFEVWIAIENRSRKPEIKASAKVRYVRFSQRAFTDGIQEKRIDQLKVRVYSPAKTVADCFKYRNKIGLDT
ALEALREGWREKRFTMDELWKYAKVCRVSNVMQPYLESITAL

Nucleotide

• Length: 609 bp

>AT75904 NZ_CP021023:2501452-2502060 [Sedimentisphaera salicampi]
ATGGGAATAAAGGCTCAAAAACTTATCGAAAATCTTAGGCAGTATGGGATGCTCAAAACAGGAGAAATCGTTGAGCTTGG
CATCTCGAAGGAGTATCTTCGAAAGCTTACGGTACAAGGAACTGTGGAGAGGGTTTCCCGCGGCCTCTACACTCTTCCCA
ACAATGATTACTCGCCAATGCAGAGCATTGCTGAGGTTTCAAAACAGGTGCCCAAAGGTGTAATCTGCCTTCTTTCTGCT
CTGCGTTTTCACGGATTTACAACACAGAATCCATTTGAGGTTTGGATTGCGATAGAAAATCGTTCCCGCAAACCCGAAAT
TAAAGCTTCTGCTAAGGTGAGGTATGTTCGGTTTTCGCAAAGAGCATTTACCGACGGGATACAGGAGAAACGGATAGATC
AGCTTAAGGTGCGAGTTTATTCGCCGGCAAAGACGGTGGCGGATTGTTTTAAATATCGCAACAAGATAGGGCTGGATACG
GCTCTGGAAGCCCTTAGAGAAGGCTGGCGGGAAAAGCGTTTTACAATGGATGAGCTTTGGAAATACGCCAAAGTGTGCAG
GGTGAGCAATGTGATGCAGCCATATCTTGAAAGCATTACTGCATTATGA