Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 1693001..1693545 Replicon chromosome
Accession NZ_CP021018
Organism Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6167

Toxin (Protein)


Gene name relE Uniprot ID A0A808FED4
Locus tag XcfCFBP6167P_RS07530 Protein ID WP_022557812.1
Coordinates 1693246..1693545 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A828YMS8
Locus tag XcfCFBP6167P_RS07525 Protein ID WP_005912560.1
Coordinates 1693001..1693258 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcfCFBP6167P_RS07510 1688104..1689603 - 1500 WP_046735535.1 ribonuclease H-like domain-containing protein -
XcfCFBP6167P_RS07515 1689600..1692095 - 2496 WP_022557810.1 DEAD/DEAH box helicase -
XcfCFBP6167P_RS07520 1692273..1692935 + 663 WP_029818121.1 hemolysin III family protein -
XcfCFBP6167P_RS07525 1693001..1693258 + 258 WP_005912560.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
XcfCFBP6167P_RS07530 1693246..1693545 + 300 WP_022557812.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XcfCFBP6167P_RS07540 1693725..1694624 - 900 WP_022557813.1 SDR family NAD(P)-dependent oxidoreductase -
XcfCFBP6167P_RS07545 1694684..1695421 - 738 WP_022557814.1 SDR family oxidoreductase -
XcfCFBP6167P_RS07550 1695547..1696458 + 912 WP_039732218.1 LysR family transcriptional regulator -
XcfCFBP6167P_RS07555 1696673..1697737 - 1065 WP_033481295.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11279.07 Da        Isoelectric Point: 10.1539

>T75899 WP_022557812.1 NZ_CP021018:1693246-1693545 [Xanthomonas citri pv. phaseoli var. fuscans]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIERPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VLVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T75899 NZ_CP021018:1693246-1693545 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATCGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATCGAACGCCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGCTGGTGCACGTAATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9646.15 Da        Isoelectric Point: 8.6223

>AT75899 WP_005912560.1 NZ_CP021018:1693001-1693258 [Xanthomonas citri pv. phaseoli var. fuscans]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT75899 NZ_CP021018:1693001-1693258 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGGGGAGAAATGGCAGTCGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A808FED4

Antitoxin

Source ID Structure
AlphaFold DB A0A828YMS8

References