75897

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 1116164..1116525 Replicon chromosome
Accession NZ_CP021018
Organism Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6167

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XcfCFBP6167P_RS05015 Protein ID WP_005914328.1
Coordinates 1116164..1116298 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XcfCFBP6167P_RS05020 Protein ID WP_003486606.1
Coordinates 1116373..1116525 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcfCFBP6167P_RS04995 1111856..1112899 - 1044 WP_033481136.1 MBL fold metallo-hydrolase -
XcfCFBP6167P_RS05000 1112929..1114218 - 1290 WP_022560228.1 tryptophan--tRNA ligase -
XcfCFBP6167P_RS05005 1114435..1115661 + 1227 WP_099868307.1 IS256-like element ISXax1 family transposase -
XcfCFBP6167P_RS05010 1115728..1115937 - 210 WP_016904514.1 CsbD family protein -
XcfCFBP6167P_RS05015 1116164..1116298 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XcfCFBP6167P_RS05020 1116373..1116525 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XcfCFBP6167P_RS05025 1116632..1117555 - 924 WP_046735866.1 arginase -
XcfCFBP6167P_RS05030 1117876..1118328 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
XcfCFBP6167P_RS05035 1118392..1118751 + 360 WP_003486613.1 hypothetical protein -
XcfCFBP6167P_RS05040 1118848..1119762 + 915 WP_022560229.1 hypothetical protein -
XcfCFBP6167P_RS05045 1119759..1120301 + 543 WP_003486615.1 GTPase -
XcfCFBP6167P_RS05050 1120781..1121464 + 684 WP_007966938.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1114435..1115661 1226


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T75897 WP_005914328.1 NZ_CP021018:c1116298-1116164 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T75897 NZ_CP021018:c1116298-1116164 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT75897 WP_003486606.1 NZ_CP021018:c1116525-1116373 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT75897 NZ_CP021018:c1116525-1116373 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References