Detailed information of TA system TA075892

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 2681017..2681561
• Replicon: chromosome
• Accession: NZ_CP021015
• Organism: Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6991

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A7X9UUA0
• Locus tag: XcfCFBP6991P_RS12255
• Protein ID: WP_033479617.1
• Coordinates: 2681017..2681316 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: XcfCFBP6991P_RS12260
• Protein ID: WP_099802649.1
• Coordinates: 2681304..2681561 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XcfCFBP6991P_RS12225	2676491..2676967	-	477	WP_099802653.1	hypothetical protein	-
XcfCFBP6991P_RS12230	2677193..2677903	-	711	WP_099802652.1	hypothetical protein	-
XcfCFBP6991P_RS12235	2678104..2679015	-	912	WP_099802651.1	LysR family transcriptional regulator	-
XcfCFBP6991P_RS12240	2679141..2679878	+	738	WP_099802650.1	SDR family oxidoreductase	-
XcfCFBP6991P_RS12245	2679938..2680837	+	900	WP_007973076.1	SDR family NAD(P)-dependent oxidoreductase	-
XcfCFBP6991P_RS12255	2681017..2681316	-	300	WP_033479617.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
XcfCFBP6991P_RS12260	2681304..2681561	-	258	WP_099802649.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
XcfCFBP6991P_RS12265	2681628..2682290	-	663	WP_162808327.1	hemolysin III family protein	-
XcfCFBP6991P_RS12270	2682468..2684963	+	2496	WP_162808326.1	DEAD/DEAH box helicase	-
XcfCFBP6991P_RS12275	2684960..2686435	+	1476	WP_099802648.1	ribonuclease H-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11246.00 Da
• Isoelectric Point: 9.7235

>T75892 WP_033479617.1 NZ_CP021015:c2681316-2681017 [Xanthomonas citri pv. phaseoli var. fuscans]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHVMRSERALRGNRLSR

Nucleotide

• Length: 300 bp

>T75892 NZ_CP021015:c2681316-2681017 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATCGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATTGAACACCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGGTGGTGCACGTAATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9618.09 Da
• Isoelectric Point: 8.6223

>AT75892 WP_099802649.1 NZ_CP021015:c2681561-2681304 [Xanthomonas citri pv. phaseoli var. fuscans]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMGVADGRTLSHEQAQQRM
ARWLK

Nucleotide

• Length: 258 bp

>AT75892 NZ_CP021015:c2681561-2681304 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGGGGAGAAATGGGAGTCGCGGACGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Structures

Toxin

• AlphaFold DB: A0A7X9UUA0