75889

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4700653..4701014 Replicon chromosome
Accession NZ_CP021012
Organism Xanthomonas citri pv. phaseoli var. fuscans strain CFBP7767

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XcfCFBP7767P_RS20275 Protein ID WP_005914328.1
Coordinates 4700653..4700787 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XcfCFBP7767P_RS20280 Protein ID WP_003486606.1
Coordinates 4700862..4701014 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcfCFBP7767P_RS20260 (XcfCFBP7767P_20765) 4697682..4698725 - 1044 WP_033481136.1 MBL fold metallo-hydrolase -
XcfCFBP7767P_RS20265 (XcfCFBP7767P_20770) 4698755..4700044 - 1290 WP_022560228.1 tryptophan--tRNA ligase -
XcfCFBP7767P_RS20270 (XcfCFBP7767P_20775) 4700217..4700426 - 210 WP_016904514.1 CsbD family protein -
XcfCFBP7767P_RS20275 (XcfCFBP7767P_20780) 4700653..4700787 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XcfCFBP7767P_RS20280 (XcfCFBP7767P_20785) 4700862..4701014 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XcfCFBP7767P_RS20285 (XcfCFBP7767P_20790) 4701121..4702044 - 924 WP_007966941.1 arginase -
XcfCFBP7767P_RS20290 (XcfCFBP7767P_20795) 4702365..4702817 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
XcfCFBP7767P_RS20295 (XcfCFBP7767P_20800) 4702881..4703240 + 360 WP_003486613.1 hypothetical protein -
XcfCFBP7767P_RS20300 (XcfCFBP7767P_20805) 4703337..4704251 + 915 WP_022560229.1 hypothetical protein -
XcfCFBP7767P_RS20305 (XcfCFBP7767P_20810) 4704248..4704790 + 543 WP_003486615.1 GTPase -
XcfCFBP7767P_RS20310 (XcfCFBP7767P_20815) 4705270..4705953 + 684 WP_007966938.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T75889 WP_005914328.1 NZ_CP021012:c4700787-4700653 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T75889 NZ_CP021012:c4700787-4700653 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT75889 WP_003486606.1 NZ_CP021012:c4701014-4700862 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT75889 NZ_CP021012:c4701014-4700862 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References