Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 2338205..2338749 Replicon chromosome
Accession NZ_CP021006
Organism Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6975

Toxin (Protein)


Gene name relE Uniprot ID A0A808FED4
Locus tag XcfCFBP6975P_RS10630 Protein ID WP_022557812.1
Coordinates 2338450..2338749 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A828YMS8
Locus tag XcfCFBP6975P_RS10625 Protein ID WP_005912560.1
Coordinates 2338205..2338462 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcfCFBP6975P_RS10610 2333320..2334807 - 1488 WP_022557809.1 ribonuclease H-like domain-containing protein -
XcfCFBP6975P_RS10615 2334804..2337299 - 2496 WP_022557810.1 DEAD/DEAH box helicase -
XcfCFBP6975P_RS10620 2337477..2338139 + 663 WP_029818121.1 hemolysin III family protein -
XcfCFBP6975P_RS10625 2338205..2338462 + 258 WP_005912560.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
XcfCFBP6975P_RS10630 2338450..2338749 + 300 WP_022557812.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XcfCFBP6975P_RS10640 2338929..2339828 - 900 WP_022557813.1 SDR family NAD(P)-dependent oxidoreductase -
XcfCFBP6975P_RS10645 2339888..2340625 - 738 WP_022557814.1 SDR family oxidoreductase -
XcfCFBP6975P_RS10650 2340751..2341662 + 912 WP_099770880.1 LysR family transcriptional regulator -
XcfCFBP6975P_RS10660 2341877..2342941 - 1065 WP_033481295.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11279.07 Da        Isoelectric Point: 10.1539

>T75884 WP_022557812.1 NZ_CP021006:2338450-2338749 [Xanthomonas citri pv. phaseoli var. fuscans]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIERPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VLVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T75884 NZ_CP021006:2338450-2338749 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATCGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATCGAACGCCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGCTGGTGCACGTAATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9646.15 Da        Isoelectric Point: 8.6223

>AT75884 WP_005912560.1 NZ_CP021006:2338205-2338462 [Xanthomonas citri pv. phaseoli var. fuscans]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT75884 NZ_CP021006:2338205-2338462 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGGGGAGAAATGGCAGTCGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A808FED4

Antitoxin

Source ID Structure
AlphaFold DB A0A828YMS8

References