Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafQ-RelB |
| Location | 2220273..2220810 | Replicon | chromosome |
| Accession | NZ_CP021006 | ||
| Organism | Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6975 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A7X9YU06 |
| Locus tag | XcfCFBP6975P_RS10060 | Protein ID | WP_017158383.1 |
| Coordinates | 2220529..2220810 (+) | Length | 94 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A7X9UWY6 |
| Locus tag | XcfCFBP6975P_RS10055 | Protein ID | WP_017158384.1 |
| Coordinates | 2220273..2220542 (+) | Length | 90 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| XcfCFBP6975P_RS10025 | 2215535..2216143 | + | 609 | WP_017154888.1 | hypothetical protein | - |
| XcfCFBP6975P_RS10030 | 2216256..2216888 | + | 633 | WP_007966093.1 | ParA family protein | - |
| XcfCFBP6975P_RS10035 | 2216881..2217213 | + | 333 | WP_007966095.1 | hypothetical protein | - |
| XcfCFBP6975P_RS10040 | 2217280..2217564 | + | 285 | WP_017154887.1 | hypothetical protein | - |
| XcfCFBP6975P_RS10045 | 2217571..2218758 | + | 1188 | WP_022560475.1 | zeta toxin family protein | - |
| XcfCFBP6975P_RS10050 | 2219202..2220164 | + | 963 | WP_022560476.1 | recombinase family protein | - |
| XcfCFBP6975P_RS10055 | 2220273..2220542 | + | 270 | WP_017158384.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| XcfCFBP6975P_RS10060 | 2220529..2220810 | + | 282 | WP_017158383.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
| XcfCFBP6975P_RS10065 | 2220948..2221301 | - | 354 | WP_033481414.1 | hypothetical protein | - |
| XcfCFBP6975P_RS10070 | 2221347..2222054 | - | 708 | WP_022560478.1 | hypothetical protein | - |
| XcfCFBP6975P_RS10075 | 2222051..2222497 | - | 447 | WP_033481413.1 | hypothetical protein | - |
| XcfCFBP6975P_RS10080 | 2222843..2223238 | + | 396 | WP_022560480.1 | hypothetical protein | - |
| XcfCFBP6975P_RS10085 | 2223336..2223605 | + | 270 | WP_033481412.1 | hypothetical protein | - |
| XcfCFBP6975P_RS10090 | 2223602..2223895 | + | 294 | WP_011345592.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| XcfCFBP6975P_RS10095 | 2224008..2224628 | + | 621 | WP_011345593.1 | hypothetical protein | - |
| XcfCFBP6975P_RS10100 | 2224827..2225168 | + | 342 | WP_029561219.1 | hypothetical protein | - |
| XcfCFBP6975P_RS10105 | 2225240..2225437 | + | 198 | WP_022560481.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 2216256..2244280 | 28024 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10679.06 Da Isoelectric Point: 8.9188
>T75883 WP_017158383.1 NZ_CP021006:2220529-2220810 [Xanthomonas citri pv. phaseoli var. fuscans]
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG
Download Length: 282 bp
>T75883 NZ_CP021006:2220529-2220810 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGCGGACGATTGACCGTTCATCCGCTTTCAAGCGCGACTACAAGCGGGAAGCCAAGGGGCAGCATCGCGCCACGCTTGA
TGACGCGATCAAGCCGGTGTTGGTCGCACTGGCGACCGATCAGCCTCCCGATGCACGCTATCGCGATCACGATCTTTCCG
GCGATTGGGCGGGCTATCGGGAATGTCACATCAAGCCTGACTTGCTGCTGATCTACCGCAAGTCCGACCCCGACACCCTG
CGACTGGCACGGCTTGGCTCGCACAGCGAGCTTTTCGGCTGA
ATGCGGACGATTGACCGTTCATCCGCTTTCAAGCGCGACTACAAGCGGGAAGCCAAGGGGCAGCATCGCGCCACGCTTGA
TGACGCGATCAAGCCGGTGTTGGTCGCACTGGCGACCGATCAGCCTCCCGATGCACGCTATCGCGATCACGATCTTTCCG
GCGATTGGGCGGGCTATCGGGAATGTCACATCAAGCCTGACTTGCTGCTGATCTACCGCAAGTCCGACCCCGACACCCTG
CGACTGGCACGGCTTGGCTCGCACAGCGAGCTTTTCGGCTGA
Antitoxin
Download Length: 90 a.a. Molecular weight: 9719.10 Da Isoelectric Point: 5.6976
>AT75883 WP_017158384.1 NZ_CP021006:2220273-2220542 [Xanthomonas citri pv. phaseoli var. fuscans]
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD
Download Length: 270 bp
>AT75883 NZ_CP021006:2220273-2220542 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAGCACTACCGCCGATACCTACGTCCGCGCCCGCATCGACACCGCCACCAAGGAACGTGCCGCTAGTGCGCTCGAAGC
AATGGGGCTGTCGATCTCTGATGCTATCCGCCTGCTGATGCTACGCATTGCCGACGAACACCGCCTGCCCTTCGATGTGA
AGGTACCAAACACCACCACGAAAAAGGCGATTGCCGAACTGGAATCAGGCAAGGGTAAGAAGTTCGCCAATGTGGACGAC
CTGATGGCGGATTTGCATGCGGACGATTGA
ATGAGCACTACCGCCGATACCTACGTCCGCGCCCGCATCGACACCGCCACCAAGGAACGTGCCGCTAGTGCGCTCGAAGC
AATGGGGCTGTCGATCTCTGATGCTATCCGCCTGCTGATGCTACGCATTGCCGACGAACACCGCCTGCCCTTCGATGTGA
AGGTACCAAACACCACCACGAAAAAGGCGATTGCCGAACTGGAATCAGGCAAGGGTAAGAAGTTCGCCAATGTGGACGAC
CTGATGGCGGATTTGCATGCGGACGATTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A7X9YU06 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A7X9UWY6 |