Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 4028984..4029521 Replicon chromosome
Accession NZ_CP021001
Organism Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6166

Toxin (Protein)


Gene name relE Uniprot ID A0A7X9YU06
Locus tag XcfCFBP6166P_RS17950 Protein ID WP_017158383.1
Coordinates 4029240..4029521 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7X9UWY6
Locus tag XcfCFBP6166P_RS17945 Protein ID WP_017158384.1
Coordinates 4028984..4029253 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcfCFBP6166P_RS17915 4024246..4024854 + 609 WP_017154888.1 hypothetical protein -
XcfCFBP6166P_RS17920 4024967..4025599 + 633 WP_007966093.1 ParA family protein -
XcfCFBP6166P_RS17925 4025592..4025924 + 333 WP_007966095.1 hypothetical protein -
XcfCFBP6166P_RS17930 4025991..4026275 + 285 WP_017154887.1 hypothetical protein -
XcfCFBP6166P_RS17935 4026282..4027469 + 1188 WP_022560475.1 zeta toxin family protein -
XcfCFBP6166P_RS17940 4027913..4028875 + 963 WP_022560476.1 recombinase family protein -
XcfCFBP6166P_RS17945 4028984..4029253 + 270 WP_017158384.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
XcfCFBP6166P_RS17950 4029240..4029521 + 282 WP_017158383.1 type II toxin-antitoxin system YafQ family toxin Toxin
XcfCFBP6166P_RS17955 4029659..4030012 - 354 WP_033481414.1 hypothetical protein -
XcfCFBP6166P_RS17960 4030058..4030765 - 708 WP_022560478.1 hypothetical protein -
XcfCFBP6166P_RS17965 4030762..4031208 - 447 WP_033481413.1 hypothetical protein -
XcfCFBP6166P_RS17970 4031554..4031949 + 396 WP_022560480.1 hypothetical protein -
XcfCFBP6166P_RS17975 4032047..4032316 + 270 WP_033481412.1 hypothetical protein -
XcfCFBP6166P_RS17980 4032313..4032606 + 294 WP_011345592.1 type II toxin-antitoxin system RelE/ParE family toxin -
XcfCFBP6166P_RS17985 4032719..4033339 + 621 WP_011345593.1 hypothetical protein -
XcfCFBP6166P_RS17990 4033538..4033879 + 342 WP_029561219.1 hypothetical protein -
XcfCFBP6166P_RS17995 4033951..4034148 + 198 WP_022560481.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4024967..4054152 29185


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-86)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10679.06 Da        Isoelectric Point: 8.9188

>T75879 WP_017158383.1 NZ_CP021001:4029240-4029521 [Xanthomonas citri pv. phaseoli var. fuscans]
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG

Download         Length: 282 bp

>T75879 NZ_CP021001:4029240-4029521 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGCGGACGATTGACCGTTCATCCGCTTTCAAGCGCGACTACAAGCGGGAAGCCAAGGGGCAGCATCGCGCCACGCTTGA
TGACGCGATCAAGCCGGTGTTGGTCGCACTGGCGACCGATCAGCCTCCCGATGCACGCTATCGCGATCACGATCTTTCCG
GCGATTGGGCGGGCTATCGGGAATGTCACATCAAGCCTGACTTGCTGCTGATCTACCGCAAGTCCGACCCCGACACCCTG
CGACTGGCACGGCTTGGCTCGCACAGCGAGCTTTTCGGCTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9719.10 Da        Isoelectric Point: 5.6976

>AT75879 WP_017158384.1 NZ_CP021001:4028984-4029253 [Xanthomonas citri pv. phaseoli var. fuscans]
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD

Download         Length: 270 bp

>AT75879 NZ_CP021001:4028984-4029253 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAGCACTACCGCCGATACCTACGTCCGCGCCCGCATCGACACCGCCACCAAGGAACGTGCCGCTAGTGCGCTCGAAGC
AATGGGGCTGTCGATCTCTGATGCTATCCGCCTGCTGATGCTACGCATTGCCGACGAACACCGCCTGCCCTTCGATGTGA
AGGTACCAAACACCACCACGAAAAAGGCGATTGCCGAACTGGAATCAGGCAAGGGTAAGAAGTTCGCCAATGTGGACGAC
CTGATGGCGGATTTGCATGCGGACGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X9YU06

Antitoxin

Source ID Structure
AlphaFold DB A0A7X9UWY6

References