Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 1940954..1941315 Replicon chromosome
Accession NZ_CP020998
Organism Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6165

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XcfCFBP6165P_RS08705 Protein ID WP_005914328.1
Coordinates 1941181..1941315 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XcfCFBP6165P_RS08700 Protein ID WP_003486606.1
Coordinates 1940954..1941106 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcfCFBP6165P_RS08670 1936012..1936695 - 684 WP_007966938.1 dTMP kinase -
XcfCFBP6165P_RS08675 1937175..1937717 - 543 WP_003486615.1 GTPase -
XcfCFBP6165P_RS08680 1937714..1938631 - 918 WP_046832402.1 hypothetical protein -
XcfCFBP6165P_RS08685 1938728..1939087 - 360 WP_003486613.1 hypothetical protein -
XcfCFBP6165P_RS08690 1939151..1939603 - 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
XcfCFBP6165P_RS08695 1939924..1940847 + 924 WP_007966941.1 arginase -
XcfCFBP6165P_RS08700 1940954..1941106 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XcfCFBP6165P_RS08705 1941181..1941315 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XcfCFBP6165P_RS08710 1941542..1941751 + 210 WP_016904514.1 CsbD family protein -
XcfCFBP6165P_RS08715 1941924..1943213 + 1290 WP_022560228.1 tryptophan--tRNA ligase -
XcfCFBP6165P_RS08720 1943243..1944286 + 1044 WP_033481136.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T75877 WP_005914328.1 NZ_CP020998:1941181-1941315 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T75877 NZ_CP020998:1941181-1941315 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT75877 WP_003486606.1 NZ_CP020998:1940954-1941106 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT75877 NZ_CP020998:1940954-1941106 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References