Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 1389453..1389997 Replicon chromosome
Accession NZ_CP020998
Organism Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6165

Toxin (Protein)


Gene name relE Uniprot ID A0A808FED4
Locus tag XcfCFBP6165P_RS06400 Protein ID WP_022557812.1
Coordinates 1389453..1389752 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A828YMS8
Locus tag XcfCFBP6165P_RS06405 Protein ID WP_005912560.1
Coordinates 1389740..1389997 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcfCFBP6165P_RS06370 1384668..1385651 - 984 WP_022557821.1 IS5-like element ISXfu1 family transposase -
XcfCFBP6165P_RS06375 1385834..1386508 - 675 Protein_1188 IS5 family transposase -
XcfCFBP6165P_RS06380 1386659..1387078 - 420 WP_099770656.1 GNAT family N-acetyltransferase -
XcfCFBP6165P_RS06385 1387511..1388491 - 981 WP_007975311.1 IS5-like element ISXfu2 family transposase -
XcfCFBP6165P_RS06390 1388551..1389273 + 723 Protein_1191 SDR family NAD(P)-dependent oxidoreductase -
XcfCFBP6165P_RS06400 1389453..1389752 - 300 WP_022557812.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XcfCFBP6165P_RS06405 1389740..1389997 - 258 WP_005912560.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
XcfCFBP6165P_RS06410 1390063..1390725 - 663 WP_029818121.1 hemolysin III family protein -
XcfCFBP6165P_RS06415 1390903..1393398 + 2496 WP_046832508.1 DEAD/DEAH box helicase -
XcfCFBP6165P_RS06420 1393395..1394894 + 1500 WP_046735535.1 ribonuclease H-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11279.07 Da        Isoelectric Point: 10.1539

>T75876 WP_022557812.1 NZ_CP020998:c1389752-1389453 [Xanthomonas citri pv. phaseoli var. fuscans]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIERPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VLVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T75876 NZ_CP020998:c1389752-1389453 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATCGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATCGAACGCCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGCTGGTGCACGTAATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9646.15 Da        Isoelectric Point: 8.6223

>AT75876 WP_005912560.1 NZ_CP020998:c1389997-1389740 [Xanthomonas citri pv. phaseoli var. fuscans]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT75876 NZ_CP020998:c1389997-1389740 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGGGGAGAAATGGCAGTCGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A808FED4

Antitoxin

Source ID Structure
AlphaFold DB A0A828YMS8

References