Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 4510478..4511022 Replicon chromosome
Accession NZ_CP020992
Organism Xanthomonas citri pv. phaseoli var. fuscans strain CFBP4885

Toxin (Protein)


Gene name relE Uniprot ID A0A808FED4
Locus tag XcfCFBP4885P_RS20210 Protein ID WP_022557812.1
Coordinates 4510478..4510777 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A828YMS8
Locus tag XcfCFBP4885P_RS20215 Protein ID WP_005912560.1
Coordinates 4510765..4511022 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcfCFBP4885P_RS20185 4506286..4507350 + 1065 WP_033481295.1 hypothetical protein -
XcfCFBP4885P_RS20190 4507565..4508476 - 912 WP_022557815.1 LysR family transcriptional regulator -
XcfCFBP4885P_RS20195 4508602..4509339 + 738 WP_022557814.1 SDR family oxidoreductase -
XcfCFBP4885P_RS20200 4509399..4510298 + 900 WP_022557813.1 SDR family NAD(P)-dependent oxidoreductase -
XcfCFBP4885P_RS20210 4510478..4510777 - 300 WP_022557812.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XcfCFBP4885P_RS20215 4510765..4511022 - 258 WP_005912560.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
XcfCFBP4885P_RS20220 4511088..4511750 - 663 WP_029818121.1 hemolysin III family protein -
XcfCFBP4885P_RS20225 4511928..4514423 + 2496 WP_022557810.1 DEAD/DEAH box helicase -
XcfCFBP4885P_RS20230 4514420..4515907 + 1488 WP_022557809.1 ribonuclease H-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11279.07 Da        Isoelectric Point: 10.1539

>T75873 WP_022557812.1 NZ_CP020992:c4510777-4510478 [Xanthomonas citri pv. phaseoli var. fuscans]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIERPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VLVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T75873 NZ_CP020992:c4510777-4510478 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATCGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATCGAACGCCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGCTGGTGCACGTAATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9646.15 Da        Isoelectric Point: 8.6223

>AT75873 WP_005912560.1 NZ_CP020992:c4511022-4510765 [Xanthomonas citri pv. phaseoli var. fuscans]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT75873 NZ_CP020992:c4511022-4510765 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGGGGAGAAATGGCAGTCGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A808FED4

Antitoxin

Source ID Structure
AlphaFold DB A0A828YMS8

References