Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 96722..97083 Replicon chromosome
Accession NZ_CP020992
Organism Xanthomonas citri pv. phaseoli var. fuscans strain CFBP4885

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XcfCFBP4885P_RS00470 Protein ID WP_005914328.1
Coordinates 96949..97083 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XcfCFBP4885P_RS00465 Protein ID WP_003486606.1
Coordinates 96722..96874 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcfCFBP4885P_RS00435 91783..92466 - 684 WP_007966938.1 dTMP kinase -
XcfCFBP4885P_RS00440 92946..93488 - 543 WP_003486615.1 GTPase -
XcfCFBP4885P_RS00445 93485..94399 - 915 WP_022560229.1 hypothetical protein -
XcfCFBP4885P_RS00450 94496..94855 - 360 WP_003486613.1 hypothetical protein -
XcfCFBP4885P_RS00455 94919..95371 - 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
XcfCFBP4885P_RS00460 95692..96615 + 924 WP_007966941.1 arginase -
XcfCFBP4885P_RS00465 96722..96874 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XcfCFBP4885P_RS00470 96949..97083 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XcfCFBP4885P_RS00475 97310..97519 + 210 WP_016904514.1 CsbD family protein -
XcfCFBP4885P_RS00480 97692..98981 + 1290 WP_022560228.1 tryptophan--tRNA ligase -
XcfCFBP4885P_RS00485 99011..100054 + 1044 WP_033481136.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T75872 WP_005914328.1 NZ_CP020992:96949-97083 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T75872 NZ_CP020992:96949-97083 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT75872 WP_003486606.1 NZ_CP020992:96722-96874 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT75872 NZ_CP020992:96722-96874 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References