75870

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3875041..3875402 Replicon chromosome
Accession NZ_CP020989
Organism Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6996R

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XcfCFBP6996P_RS16960 Protein ID WP_005914328.1
Coordinates 3875268..3875402 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XcfCFBP6996P_RS16955 Protein ID WP_003486606.1
Coordinates 3875041..3875193 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcfCFBP6996P_RS16925 3870099..3870782 - 684 WP_099803186.1 dTMP kinase -
XcfCFBP6996P_RS16930 3871262..3871804 - 543 WP_099803185.1 GTPase -
XcfCFBP6996P_RS16935 3871801..3872718 - 918 WP_007966939.1 hypothetical protein -
XcfCFBP6996P_RS16940 3872815..3873174 - 360 WP_003486613.1 hypothetical protein -
XcfCFBP6996P_RS16945 3873238..3873690 - 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
XcfCFBP6996P_RS16950 3874011..3874934 + 924 WP_007966941.1 arginase -
XcfCFBP6996P_RS16955 3875041..3875193 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XcfCFBP6996P_RS16960 3875268..3875402 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XcfCFBP6996P_RS16965 3875629..3875838 + 210 WP_016904514.1 CsbD family protein -
XcfCFBP6996P_RS16970 3876011..3877300 + 1290 WP_099803184.1 tryptophan--tRNA ligase -
XcfCFBP6996P_RS16975 3877330..3878373 + 1044 WP_099803183.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T75870 WP_005914328.1 NZ_CP020989:3875268-3875402 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T75870 NZ_CP020989:3875268-3875402 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT75870 WP_003486606.1 NZ_CP020989:3875041-3875193 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT75870 NZ_CP020989:3875041-3875193 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References