Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 3324427..3324971 Replicon chromosome
Accession NZ_CP020989
Organism Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6996R

Toxin (Protein)


Gene name relE Uniprot ID A0A7X9UUA0
Locus tag XcfCFBP6996P_RS14585 Protein ID WP_033479617.1
Coordinates 3324427..3324726 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7Z7EKF2
Locus tag XcfCFBP6996P_RS14590 Protein ID WP_029818122.1
Coordinates 3324714..3324971 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcfCFBP6996P_RS14555 3319766..3320374 + 609 WP_099803359.1 NAD(P)H-dependent oxidoreductase -
XcfCFBP6996P_RS14560 3320603..3321313 - 711 WP_099803358.1 hypothetical protein -
XcfCFBP6996P_RS14565 3321514..3322425 - 912 WP_099803357.1 LysR family transcriptional regulator -
XcfCFBP6996P_RS14570 3322551..3323288 + 738 WP_007964860.1 SDR family oxidoreductase -
XcfCFBP6996P_RS14575 3323348..3324247 + 900 WP_099803356.1 SDR family NAD(P)-dependent oxidoreductase -
XcfCFBP6996P_RS14585 3324427..3324726 - 300 WP_033479617.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XcfCFBP6996P_RS14590 3324714..3324971 - 258 WP_029818122.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
XcfCFBP6996P_RS14595 3325038..3325700 - 663 WP_029818121.1 hemolysin III family protein -
XcfCFBP6996P_RS14600 3325879..3328374 + 2496 WP_181259439.1 DEAD/DEAH box helicase -
XcfCFBP6996P_RS14605 3328371..3329852 + 1482 WP_099828349.1 ribonuclease H-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11246.00 Da        Isoelectric Point: 9.7235

>T75869 WP_033479617.1 NZ_CP020989:c3324726-3324427 [Xanthomonas citri pv. phaseoli var. fuscans]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T75869 NZ_CP020989:c3324726-3324427 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATCGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATTGAACACCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGGTGGTGCACGTAATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9632.12 Da        Isoelectric Point: 8.6223

>AT75869 WP_029818122.1 NZ_CP020989:c3324971-3324714 [Xanthomonas citri pv. phaseoli var. fuscans]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVADGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT75869 NZ_CP020989:c3324971-3324714 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGGGGAGAAATGGCAGTCGCGGACGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X9UUA0

Antitoxin

Source ID Structure
AlphaFold DB A0A7Z7EKF2

References