Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2005514..2005875 Replicon chromosome
Accession NZ_CP020987
Organism Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6994R

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XcfCFBP6994P_RS08825 Protein ID WP_005914328.1
Coordinates 2005514..2005648 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XcfCFBP6994P_RS08830 Protein ID WP_003486606.1
Coordinates 2005723..2005875 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcfCFBP6994P_RS08810 2002543..2003586 - 1044 WP_099803183.1 MBL fold metallo-hydrolase -
XcfCFBP6994P_RS08815 2003616..2004905 - 1290 WP_099803184.1 tryptophan--tRNA ligase -
XcfCFBP6994P_RS08820 2005078..2005287 - 210 WP_016904514.1 CsbD family protein -
XcfCFBP6994P_RS08825 2005514..2005648 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XcfCFBP6994P_RS08830 2005723..2005875 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XcfCFBP6994P_RS08835 2005982..2006905 - 924 WP_007966941.1 arginase -
XcfCFBP6994P_RS08840 2007226..2007678 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
XcfCFBP6994P_RS08845 2007742..2008101 + 360 WP_003486613.1 hypothetical protein -
XcfCFBP6994P_RS08850 2008198..2009115 + 918 WP_007966939.1 hypothetical protein -
XcfCFBP6994P_RS08855 2009112..2009654 + 543 WP_099803185.1 GTPase -
XcfCFBP6994P_RS08860 2010134..2010817 + 684 WP_099803186.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T75866 WP_005914328.1 NZ_CP020987:c2005648-2005514 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T75866 NZ_CP020987:c2005648-2005514 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT75866 WP_003486606.1 NZ_CP020987:c2005875-2005723 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT75866 NZ_CP020987:c2005875-2005723 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References