75863

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 6642..7003 Replicon chromosome
Accession NZ_CP020985
Organism Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6992

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XcfCFBP6992P_RS00040 Protein ID WP_005914328.1
Coordinates 6642..6776 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XcfCFBP6992P_RS00045 Protein ID WP_003486606.1
Coordinates 6851..7003 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcfCFBP6992P_RS00025 3671..4714 - 1044 WP_099803183.1 MBL fold metallo-hydrolase -
XcfCFBP6992P_RS00030 4744..6033 - 1290 WP_099803184.1 tryptophan--tRNA ligase -
XcfCFBP6992P_RS00035 6206..6415 - 210 WP_016904514.1 CsbD family protein -
XcfCFBP6992P_RS00040 6642..6776 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XcfCFBP6992P_RS00045 6851..7003 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XcfCFBP6992P_RS00050 7110..8033 - 924 WP_007966941.1 arginase -
XcfCFBP6992P_RS00055 8354..8806 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
XcfCFBP6992P_RS00060 8870..9229 + 360 WP_003486613.1 hypothetical protein -
XcfCFBP6992P_RS00065 9326..10243 + 918 WP_007966939.1 hypothetical protein -
XcfCFBP6992P_RS00070 10240..10782 + 543 WP_099803185.1 GTPase -
XcfCFBP6992P_RS00075 11262..11945 + 684 WP_099803186.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T75863 WP_005914328.1 NZ_CP020985:c6776-6642 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T75863 NZ_CP020985:c6776-6642 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT75863 WP_003486606.1 NZ_CP020985:c7003-6851 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT75863 NZ_CP020985:c7003-6851 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References