75860

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4389023..4389384 Replicon chromosome
Accession NZ_CP020983
Organism Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6990

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XcfCFBP6990P_RS19940 Protein ID WP_005914328.1
Coordinates 4389023..4389157 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XcfCFBP6990P_RS19945 Protein ID WP_003486606.1
Coordinates 4389232..4389384 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcfCFBP6990P_RS19925 4386052..4387095 - 1044 WP_099802478.1 MBL fold metallo-hydrolase -
XcfCFBP6990P_RS19930 4387125..4388414 - 1290 WP_007966942.1 tryptophan--tRNA ligase -
XcfCFBP6990P_RS19935 4388587..4388796 - 210 WP_016904514.1 CsbD family protein -
XcfCFBP6990P_RS19940 4389023..4389157 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XcfCFBP6990P_RS19945 4389232..4389384 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XcfCFBP6990P_RS19950 4389491..4390414 - 924 WP_007966941.1 arginase -
XcfCFBP6990P_RS19955 4390735..4391187 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
XcfCFBP6990P_RS19960 4391251..4391610 + 360 WP_003486613.1 hypothetical protein -
XcfCFBP6990P_RS19965 4391707..4392624 + 918 WP_007966939.1 hypothetical protein -
XcfCFBP6990P_RS19970 4392621..4393163 + 543 WP_003486615.1 GTPase -
XcfCFBP6990P_RS19975 4393647..4394330 + 684 WP_007966938.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T75860 WP_005914328.1 NZ_CP020983:c4389157-4389023 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T75860 NZ_CP020983:c4389157-4389023 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT75860 WP_003486606.1 NZ_CP020983:c4389384-4389232 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT75860 NZ_CP020983:c4389384-4389232 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGTAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References