Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4575511..4575872 Replicon chromosome
Accession NZ_CP020981
Organism Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6989

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XcfCFBP6989P_RS20445 Protein ID WP_005914328.1
Coordinates 4575738..4575872 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XcfCFBP6989P_RS20440 Protein ID WP_003486606.1
Coordinates 4575511..4575663 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcfCFBP6989P_RS20410 4570565..4571248 - 684 WP_007966938.1 dTMP kinase -
XcfCFBP6989P_RS20415 4571732..4572274 - 543 WP_003486615.1 GTPase -
XcfCFBP6989P_RS20420 4572271..4573188 - 918 WP_007966939.1 hypothetical protein -
XcfCFBP6989P_RS20425 4573285..4573644 - 360 WP_003486613.1 hypothetical protein -
XcfCFBP6989P_RS20430 4573708..4574160 - 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
XcfCFBP6989P_RS20435 4574481..4575404 + 924 WP_007966941.1 arginase -
XcfCFBP6989P_RS20440 4575511..4575663 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XcfCFBP6989P_RS20445 4575738..4575872 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XcfCFBP6989P_RS20450 4576099..4576308 + 210 WP_016904514.1 CsbD family protein -
XcfCFBP6989P_RS20455 4576481..4577770 + 1290 WP_007966942.1 tryptophan--tRNA ligase -
XcfCFBP6989P_RS20460 4577800..4578843 + 1044 WP_099802478.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T75857 WP_005914328.1 NZ_CP020981:4575738-4575872 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T75857 NZ_CP020981:4575738-4575872 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT75857 WP_003486606.1 NZ_CP020981:4575511-4575663 [Xanthomonas citri pv. phaseoli var. fuscans]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT75857 NZ_CP020981:4575511-4575663 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGTAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References