Detailed information of TA system TA075856

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 4020769..4021313
• Replicon: chromosome
• Accession: NZ_CP020981
• Organism: Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6989

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A7X9UUA0
• Locus tag: XcfCFBP6989P_RS18125
• Protein ID: WP_033479617.1
• Coordinates: 4020769..4021068 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: XcfCFBP6989P_RS18130
• Protein ID: WP_099802649.1
• Coordinates: 4021056..4021313 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XcfCFBP6989P_RS18095	4016243..4016719	-	477	WP_099802653.1	hypothetical protein	-
XcfCFBP6989P_RS18100	4016945..4017655	-	711	WP_099802652.1	hypothetical protein	-
XcfCFBP6989P_RS18105	4017856..4018767	-	912	WP_099802651.1	LysR family transcriptional regulator	-
XcfCFBP6989P_RS18110	4018893..4019630	+	738	WP_099802650.1	SDR family oxidoreductase	-
XcfCFBP6989P_RS18115	4019690..4020589	+	900	WP_007973076.1	SDR family NAD(P)-dependent oxidoreductase	-
XcfCFBP6989P_RS18125	4020769..4021068	-	300	WP_033479617.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
XcfCFBP6989P_RS18130	4021056..4021313	-	258	WP_099802649.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
XcfCFBP6989P_RS18135	4021380..4022042	-	663	WP_162808327.1	hemolysin III family protein	-
XcfCFBP6989P_RS18140	4022220..4024715	+	2496	WP_162808326.1	DEAD/DEAH box helicase	-
XcfCFBP6989P_RS18145	4024712..4026187	+	1476	WP_099802648.1	ribonuclease H-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11246.00 Da
• Isoelectric Point: 9.7235

>T75856 WP_033479617.1 NZ_CP020981:c4021068-4020769 [Xanthomonas citri pv. phaseoli var. fuscans]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHVMRSERALRGNRLSR

Nucleotide

• Length: 300 bp

>T75856 NZ_CP020981:c4021068-4020769 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATCGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATTGAACACCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGGTGGTGCACGTAATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9618.09 Da
• Isoelectric Point: 8.6223

>AT75856 WP_099802649.1 NZ_CP020981:c4021313-4021056 [Xanthomonas citri pv. phaseoli var. fuscans]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMGVADGRTLSHEQAQQRM
ARWLK

Nucleotide

• Length: 258 bp

>AT75856 NZ_CP020981:c4021313-4021056 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGGGGAGAAATGGGAGTCGCGGACGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Structures

Toxin

• AlphaFold DB: A0A7X9UUA0