Detailed information of TA system TA075851

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 582474..583018
• Replicon: chromosome
• Accession: NZ_CP020979
• Organism: Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6988R

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A7X9UUA0
• Locus tag: XcfCFBP6988P_RS02475
• Protein ID: WP_033479617.1
• Coordinates: 582719..583018 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: XcfCFBP6988P_RS02470
• Protein ID: WP_099802649.1
• Coordinates: 582474..582731 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XcfCFBP6988P_RS02455	577600..579075	-	1476	WP_099802648.1	ribonuclease H-like domain-containing protein	-
XcfCFBP6988P_RS02460	579072..581567	-	2496	WP_162808326.1	DEAD/DEAH box helicase	-
XcfCFBP6988P_RS02465	581745..582407	+	663	WP_162808327.1	hemolysin III family protein	-
XcfCFBP6988P_RS02470	582474..582731	+	258	WP_099802649.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
XcfCFBP6988P_RS02475	582719..583018	+	300	WP_033479617.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
XcfCFBP6988P_RS02485	583198..584097	-	900	WP_007973076.1	SDR family NAD(P)-dependent oxidoreductase	-
XcfCFBP6988P_RS02490	584157..584894	-	738	WP_099802650.1	SDR family oxidoreductase	-
XcfCFBP6988P_RS02495	585020..585931	+	912	WP_099802651.1	LysR family transcriptional regulator	-
XcfCFBP6988P_RS02500	586132..586842	+	711	WP_099802652.1	hypothetical protein	-
XcfCFBP6988P_RS02505	587068..587544	+	477	WP_099802653.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11246.00 Da
• Isoelectric Point: 9.7235

>T75851 WP_033479617.1 NZ_CP020979:582719-583018 [Xanthomonas citri pv. phaseoli var. fuscans]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHVMRSERALRGNRLSR

Nucleotide

• Length: 300 bp

>T75851 NZ_CP020979:582719-583018 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATCGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATTGAACACCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGGTGGTGCACGTAATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9618.09 Da
• Isoelectric Point: 8.6223

>AT75851 WP_099802649.1 NZ_CP020979:582474-582731 [Xanthomonas citri pv. phaseoli var. fuscans]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMGVADGRTLSHEQAQQRM
ARWLK

Nucleotide

• Length: 258 bp

>AT75851 NZ_CP020979:582474-582731 [Xanthomonas citri pv. phaseoli var. fuscans]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGGGGAGAAATGGGAGTCGCGGACGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Structures

Toxin

• AlphaFold DB: A0A7X9UUA0