75842

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4451531..4451892 Replicon chromosome
Accession NZ_CP020971
Organism Xanthomonas phaseoli pv. phaseoli strain CFBP6546R

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XppCFBP6546P_RS19310 Protein ID WP_005914328.1
Coordinates 4451531..4451665 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A3Q9Q401
Locus tag XppCFBP6546P_RS19315 Protein ID WP_039568455.1
Coordinates 4451740..4451892 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XppCFBP6546P_RS19285 (XppCFBP6546P_14500) 4446887..4447142 + 256 Protein_3797 hypothetical protein -
XppCFBP6546P_RS19290 (XppCFBP6546P_14495) 4447223..4448449 - 1227 WP_011345585.1 IS256-like element ISXax1 family transposase -
XppCFBP6546P_RS19295 (XppCFBP6546P_14490) 4448547..4449491 - 945 WP_039568459.1 MBL fold metallo-hydrolase -
XppCFBP6546P_RS19300 (XppCFBP6546P_14485) 4449621..4450910 - 1290 WP_039568540.1 tryptophan--tRNA ligase -
XppCFBP6546P_RS19305 (XppCFBP6546P_14480) 4451092..4451301 - 210 WP_003486601.1 CsbD family protein -
XppCFBP6546P_RS19310 (XppCFBP6546P_14475) 4451531..4451665 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XppCFBP6546P_RS19315 (XppCFBP6546P_14470) 4451740..4451892 - 153 WP_039568455.1 entericidin A/B family lipoprotein Antitoxin
XppCFBP6546P_RS19320 (XppCFBP6546P_14465) 4451999..4452922 - 924 WP_039568453.1 arginase -
XppCFBP6546P_RS19325 (XppCFBP6546P_14460) 4453243..4453695 + 453 WP_017158238.1 roadblock/LC7 domain-containing protein -
XppCFBP6546P_RS19330 (XppCFBP6546P_14455) 4453759..4454118 + 360 WP_003486613.1 hypothetical protein -
XppCFBP6546P_RS19335 (XppCFBP6546P_14450) 4454215..4455132 + 918 WP_103412531.1 hypothetical protein -
XppCFBP6546P_RS19340 (XppCFBP6546P_14445) 4455129..4455671 + 543 WP_039568446.1 GTPase -
XppCFBP6546P_RS19345 (XppCFBP6546P_14435) 4456140..4456823 + 684 WP_039568445.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 4447223..4448449 1226


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T75842 WP_005914328.1 NZ_CP020971:c4451665-4451531 [Xanthomonas phaseoli pv. phaseoli]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T75842 NZ_CP020971:c4451665-4451531 [Xanthomonas phaseoli pv. phaseoli]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5138.07 Da        Isoelectric Point: 8.7942

>AT75842 WP_039568455.1 NZ_CP020971:c4451892-4451740 [Xanthomonas phaseoli pv. phaseoli]
MKRLLTLMVLGLFSSGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT75842 NZ_CP020971:c4451892-4451740 [Xanthomonas phaseoli pv. phaseoli]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGTCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAGTGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A3Q9Q401

References