75835

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3661200..3661561 Replicon chromosome
Accession NZ_CP020964
Organism Xanthomonas phaseoli pv. phaseoli strain CFBP412

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XppCFBP412P_RS16615 Protein ID WP_005914328.1
Coordinates 3661200..3661334 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A3Q9Q401
Locus tag XppCFBP412P_RS16620 Protein ID WP_039568455.1
Coordinates 3661409..3661561 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XppCFBP412P_RS16595 3657893..3658148 + 256 Protein_3096 hypothetical protein -
XppCFBP412P_RS16600 3658216..3659250 - 1035 WP_046736011.1 MBL fold metallo-hydrolase -
XppCFBP412P_RS16605 3659290..3660579 - 1290 WP_039568540.1 tryptophan--tRNA ligase -
XppCFBP412P_RS16610 3660761..3660970 - 210 WP_003486601.1 CsbD family protein -
XppCFBP412P_RS16615 3661200..3661334 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XppCFBP412P_RS16620 3661409..3661561 - 153 WP_039568455.1 entericidin A/B family lipoprotein Antitoxin
XppCFBP412P_RS16625 3661668..3662591 - 924 WP_039568453.1 arginase -
XppCFBP412P_RS16630 3662912..3663364 + 453 WP_017158238.1 roadblock/LC7 domain-containing protein -
XppCFBP412P_RS16635 3663428..3663787 + 360 WP_003486613.1 hypothetical protein -
XppCFBP412P_RS16640 3663884..3664801 + 918 WP_039568451.1 hypothetical protein -
XppCFBP412P_RS16645 3664798..3665340 + 543 WP_039568446.1 GTPase -
XppCFBP412P_RS16655 3665809..3666492 + 684 WP_039568445.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T75835 WP_005914328.1 NZ_CP020964:c3661334-3661200 [Xanthomonas phaseoli pv. phaseoli]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T75835 NZ_CP020964:c3661334-3661200 [Xanthomonas phaseoli pv. phaseoli]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5138.07 Da        Isoelectric Point: 8.7942

>AT75835 WP_039568455.1 NZ_CP020964:c3661561-3661409 [Xanthomonas phaseoli pv. phaseoli]
MKRLLTLMVLGLFSSGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT75835 NZ_CP020964:c3661561-3661409 [Xanthomonas phaseoli pv. phaseoli]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGTCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAGTGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A3Q9Q401

References