Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 278933..279603 Replicon plasmid pRheCIAT894e
Accession NZ_CP020952
Organism Rhizobium sp. CIAT894

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RHEC894_RS30225 Protein ID WP_085740333.1
Coordinates 279199..279603 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RHEC894_RS30220 Protein ID WP_085740332.1
Coordinates 278933..279202 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RHEC894_RS30200 274691..276055 + 1365 Protein_249 aldehyde dehydrogenase (NADP(+)) -
RHEC894_RS30205 276061..276255 - 195 Protein_250 dihydrodipicolinate synthase family protein -
RHEC894_RS30210 276919..277467 - 549 WP_085740330.1 hypothetical protein -
RHEC894_RS30215 277596..278270 - 675 WP_085740331.1 transcriptional regulator -
RHEC894_RS33210 278668..278832 + 165 WP_164517729.1 hypothetical protein -
RHEC894_RS30220 278933..279202 + 270 WP_085740332.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
RHEC894_RS30225 279199..279603 + 405 WP_085740333.1 type II toxin-antitoxin system VapC family toxin Toxin
RHEC894_RS30230 279729..280754 - 1026 WP_085740334.1 ABC transporter permease -
RHEC894_RS30235 280796..282337 - 1542 WP_085740335.1 sugar ABC transporter ATP-binding protein -
RHEC894_RS30240 282416..283378 - 963 WP_085740336.1 sugar-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..718394 718394


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-117)

Antitoxin

SpoVT-AbrB domain

(18-53)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14163.52 Da        Isoelectric Point: 5.8527

>T75766 WP_085740333.1 NZ_CP020952:279199-279603 [Rhizobium sp. CIAT894]
VSRLYMLDTNIVSELARNPRGVVARRIAEVGPDAICVSIITASELRYGCAKKGSPKLLAQIEAILGSLAVLALDVPADDA
YGGIRAELEAAGKPIGPNDLFIAAHASALGAVLVTANISEFMRIRPLQVENWLV

Download         Length: 405 bp

>T75766 NZ_CP020952:279199-279603 [Rhizobium sp. CIAT894]
GTGAGCAGGCTTTATATGCTGGACACCAATATCGTCTCCGAGCTTGCCCGAAACCCGAGGGGTGTCGTCGCTCGGCGCAT
CGCCGAGGTTGGCCCCGATGCAATCTGCGTCAGTATTATCACGGCGTCGGAGTTACGCTACGGGTGCGCCAAAAAGGGAT
CACCGAAACTTCTAGCACAGATCGAAGCTATCCTTGGCAGCTTAGCGGTGCTTGCGCTGGATGTACCCGCCGATGATGCA
TACGGCGGCATCCGAGCTGAACTAGAGGCCGCTGGCAAGCCTATCGGTCCGAATGACCTATTTATCGCCGCCCACGCCTC
CGCCCTCGGAGCAGTTCTGGTGACGGCCAACATAAGCGAGTTCATGCGTATTCGCCCTTTGCAGGTCGAAAACTGGTTGG
TTTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10241.77 Da        Isoelectric Point: 4.8728

>AT75766 WP_085740332.1 NZ_CP020952:278933-279202 [Rhizobium sp. CIAT894]
MAHFRQQEPIPPREAKLFRNNKSQAVRIPADFELPGDRVMIHRDGDRLIIEPVHRKNLLEVLAGLEPLGPEDQFPDVDDT
LLPLKEIDL

Download         Length: 270 bp

>AT75766 NZ_CP020952:278933-279202 [Rhizobium sp. CIAT894]
ATGGCCCATTTTCGACAACAAGAGCCTATTCCCCCGAGGGAGGCCAAGCTTTTCAGAAACAACAAGAGTCAGGCTGTGCG
AATCCCGGCCGACTTTGAGCTACCCGGCGACCGAGTGATGATCCACCGCGACGGCGATCGGCTGATTATAGAGCCTGTGC
ACCGCAAGAACCTCCTGGAAGTCCTGGCAGGTTTGGAGCCGCTTGGCCCTGAAGATCAGTTCCCTGATGTAGACGATACC
CTGCTTCCTTTGAAGGAAATCGACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References