Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 191268..192058 Replicon plasmid pRheCIAT894d
Accession NZ_CP020951
Organism Rhizobium sp. CIAT894

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag RHEC894_RS27240 Protein ID WP_085739839.1
Coordinates 191561..192058 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag RHEC894_RS27235 Protein ID WP_085739838.1
Coordinates 191268..191564 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RHEC894_RS27215 186789..188210 - 1422 WP_085739834.1 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme -
RHEC894_RS27220 188234..188917 - 684 WP_085739835.1 MtnX-like HAD-IB family phosphatase -
RHEC894_RS27225 189052..190428 - 1377 WP_085739836.1 sensor histidine kinase N-terminal domain-containing protein -
RHEC894_RS27230 190425..191081 - 657 WP_085739837.1 response regulator transcription factor -
RHEC894_RS27235 191268..191564 + 297 WP_085739838.1 DUF1778 domain-containing protein Antitoxin
RHEC894_RS27240 191561..192058 + 498 WP_085739839.1 GNAT family N-acetyltransferase Toxin
RHEC894_RS27245 192099..192935 - 837 WP_085739840.1 ABC transporter ATP-binding protein -
RHEC894_RS27250 192905..193894 - 990 WP_085739841.1 ABC transporter ATP-binding protein -
RHEC894_RS27255 193896..194753 - 858 WP_085739842.1 ABC transporter permease -
RHEC894_RS27260 194757..195761 - 1005 WP_085739843.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..560456 560456


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-142)

Antitoxin

Vibrio phage ICP1, Orf50

(6-97)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17667.18 Da        Isoelectric Point: 6.8716

>T75765 WP_085739839.1 NZ_CP020951:191561-192058 [Rhizobium sp. CIAT894]
VTLSPPAPLADHHELAEFSSGVPELDNWLRRRARANQAGGASRTFVVCEGNQVIAYYALASGAVKQPEAPGRFRRNMPDP
IPVAVLGRLAIDQSYQGRGIGRALVRDAGLRLLNAAEILGIRGVLVHAISDDARAFYEAVGFLPSPSDPMMLMVGLHDLD
SALNS

Download         Length: 498 bp

>T75765 NZ_CP020951:191561-192058 [Rhizobium sp. CIAT894]
GTGACCCTCAGCCCGCCGGCACCCCTGGCCGATCATCACGAACTGGCCGAATTCAGTTCCGGCGTGCCTGAACTGGATAA
TTGGCTGCGTCGCCGTGCCCGCGCCAATCAGGCAGGCGGCGCATCGCGTACCTTTGTCGTGTGCGAGGGAAACCAAGTCA
TTGCCTATTATGCGCTTGCTTCAGGCGCGGTAAAGCAGCCGGAAGCGCCCGGCCGTTTTCGGCGGAACATGCCTGATCCG
ATTCCGGTTGCCGTACTTGGCCGCCTCGCTATCGATCAATCTTACCAGGGTCGGGGCATCGGCAGGGCATTGGTGCGCGA
TGCGGGCCTGCGGCTGCTCAATGCTGCAGAAATCCTCGGCATCCGCGGCGTGCTGGTGCATGCGATTTCCGACGATGCGC
GAGCCTTCTACGAAGCGGTCGGCTTTCTGCCCTCGCCATCCGACCCCATGATGCTGATGGTCGGATTGCATGACCTTGAT
AGCGCGCTGAACTCGTGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11002.60 Da        Isoelectric Point: 9.9187

>AT75765 WP_085739838.1 NZ_CP020951:191268-191564 [Rhizobium sp. CIAT894]
MPASPTNKSPDASVPLNMRIKPATRNLIDRAAELLGKTRTDFMLEASERRAEEVLLNRTIFTVSPEIHAEYLARLDAPTQ
PNARLKRTMSTKAPWDEA

Download         Length: 297 bp

>AT75765 NZ_CP020951:191268-191564 [Rhizobium sp. CIAT894]
ATGCCCGCCTCACCGACAAACAAAAGTCCGGACGCAAGCGTGCCGCTGAATATGCGCATTAAGCCTGCGACCCGCAACTT
GATCGATCGCGCCGCCGAGTTGCTGGGAAAGACCCGCACGGATTTTATGCTGGAGGCTTCCGAGCGCCGCGCCGAGGAAG
TGCTGCTCAACCGTACCATATTCACGGTCAGCCCCGAAATCCATGCCGAATACCTTGCCCGCCTGGATGCGCCCACACAG
CCGAATGCGCGCCTGAAACGGACCATGTCGACCAAAGCGCCATGGGATGAGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References