Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 112288..112858 Replicon plasmid pRheCIAT894c
Accession NZ_CP020950
Organism Rhizobium sp. CIAT894

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag RHEC894_RS24545 Protein ID WP_085739593.1
Coordinates 112574..112858 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag RHEC894_RS24540 Protein ID WP_085739592.1
Coordinates 112288..112587 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RHEC894_RS24525 109052..109225 - 174 WP_085739590.1 HU family DNA-binding protein -
RHEC894_RS33110 109630..109797 + 168 WP_003594538.1 hypothetical protein -
RHEC894_RS24530 109887..110222 - 336 WP_085739689.1 WGR domain-containing protein -
RHEC894_RS24535 110672..111148 + 477 WP_085739591.1 hypothetical protein -
RHEC894_RS24540 112288..112587 + 300 WP_085739592.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
RHEC894_RS24545 112574..112858 + 285 WP_085739593.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RHEC894_RS24550 113022..113258 + 237 WP_085739594.1 hypothetical protein -
RHEC894_RS24555 113499..113906 + 408 WP_085739595.1 hypothetical protein -
RHEC894_RS24560 114244..114684 + 441 WP_010067432.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - htpB / hsiC1/vipB 1..464024 464024


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-56)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10899.34 Da        Isoelectric Point: 4.8552

>T75763 WP_085739593.1 NZ_CP020950:112574-112858 [Rhizobium sp. CIAT894]
VPELEWLETARADLLAIIDYISDDNPDAAQRLKDDIETKAAKLPEHPRLYRSGRVEGTREMIVRANYIVVYTEDPYTVRI
LRVLHAAQQWPPQN

Download         Length: 285 bp

>T75763 NZ_CP020950:112574-112858 [Rhizobium sp. CIAT894]
GTGCCCGAGCTTGAATGGTTGGAAACAGCTCGAGCCGATCTACTGGCGATTATCGACTACATCTCTGACGACAATCCCGA
CGCCGCGCAAAGGTTGAAAGATGATATCGAGACCAAAGCCGCAAAGCTGCCGGAGCACCCCCGACTTTACCGGTCCGGTC
GTGTCGAAGGTACGCGGGAAATGATCGTGCGGGCAAACTACATCGTTGTATACACGGAAGATCCCTACACGGTGCGTATC
CTGCGTGTGCTGCACGCCGCCCAACAATGGCCACCGCAAAATTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10989.51 Da        Isoelectric Point: 8.8605

>AT75763 WP_085739592.1 NZ_CP020950:112288-112587 [Rhizobium sp. CIAT894]
MAAHTSMLHIRVDDKLKADATETLANFGLSVSDAVRIFLTRVAKEGGLPAGLTTDPEAHDEWFRAKVREALADTRPSVPH
RQVMDEAQALIDRKRRARA

Download         Length: 300 bp

>AT75763 NZ_CP020950:112288-112587 [Rhizobium sp. CIAT894]
ATGGCCGCACACACATCCATGCTGCACATTCGAGTAGACGACAAGCTCAAGGCCGACGCCACCGAAACGCTCGCCAATTT
CGGATTGTCCGTCTCGGATGCCGTGCGGATCTTCCTGACCCGCGTCGCCAAGGAGGGCGGCTTACCGGCCGGCCTGACGA
CCGACCCGGAAGCCCACGACGAATGGTTCCGTGCCAAGGTGCGCGAGGCTCTGGCCGATACTCGACCAAGCGTGCCGCAT
CGACAGGTCATGGACGAGGCACAAGCATTGATCGACAGGAAGCGCCGTGCCCGAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References