Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 1022453..1022930 Replicon chromosome
Accession NZ_CP020947
Organism Rhizobium sp. CIAT894

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag RHEC894_RS05005 Protein ID WP_085736488.1
Coordinates 1022661..1022930 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag RHEC894_RS05000 Protein ID WP_010069011.1
Coordinates 1022453..1022677 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RHEC894_RS04970 1018674..1019039 - 366 WP_085736486.1 nuclear transport factor 2 family protein -
RHEC894_RS04975 1019044..1019658 - 615 WP_085738858.1 HAD family phosphatase -
RHEC894_RS04980 1019661..1020764 - 1104 WP_085736487.1 A/G-specific adenine glycosylase -
RHEC894_RS04985 1020872..1021369 + 498 WP_010069014.1 DUF721 domain-containing protein -
RHEC894_RS04990 1021369..1021563 + 195 WP_010069013.1 hypothetical protein -
RHEC894_RS04995 1021614..1021976 - 363 WP_010069012.1 hypothetical protein -
RHEC894_RS05000 1022453..1022677 + 225 WP_010069011.1 TraY domain-containing protein Antitoxin
RHEC894_RS05005 1022661..1022930 + 270 WP_085736488.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RHEC894_RS05010 1023080..1023856 + 777 WP_085736489.1 DsbA family protein -
RHEC894_RS05015 1024076..1027537 + 3462 WP_085736490.1 chromosome segregation protein SMC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-88)

Antitoxin

Relaxosome protein TraY

(4-49)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10442.95 Da        Isoelectric Point: 10.4069

>T75759 WP_085736488.1 NZ_CP020947:1022661-1022930 [Rhizobium sp. CIAT894]
MAWRIEFQRAAERELEKLGHEAARRILRFLNDRVARLDDPRSIGEALKGSELGDFWKYRVGDYRVIASIDDGAVRILVVR
IGNRRDVYR

Download         Length: 270 bp

>T75759 NZ_CP020947:1022661-1022930 [Rhizobium sp. CIAT894]
ATGGCGTGGAGAATTGAGTTTCAAAGGGCAGCCGAGCGCGAGCTTGAGAAGCTTGGACATGAGGCGGCGCGCCGAATACT
CCGATTTCTCAATGACCGCGTGGCGAGACTAGATGATCCACGATCCATTGGAGAGGCGCTTAAAGGGTCTGAACTCGGGG
ATTTCTGGAAATATCGCGTTGGCGACTATCGAGTGATCGCAAGCATCGACGACGGGGCCGTTCGTATCCTCGTTGTTCGT
ATCGGCAACCGCCGTGACGTCTACCGATGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8607.76 Da        Isoelectric Point: 4.6909

>AT75759 WP_010069011.1 NZ_CP020947:1022453-1022677 [Rhizobium sp. CIAT894]
MLALRLPPEIEARLDELSKRTGRSKSFYARQAILEHLDDLEDVYLAEKRLEELRRGESDTVSLAELMTRYGVEN

Download         Length: 225 bp

>AT75759 NZ_CP020947:1022453-1022677 [Rhizobium sp. CIAT894]
ATGTTGGCTTTGCGGTTGCCGCCTGAAATCGAAGCTCGGCTCGACGAGCTTTCCAAGCGCACGGGCCGCAGCAAGAGCTT
CTATGCCCGTCAGGCCATTCTCGAACATCTCGATGACCTTGAGGACGTCTATCTCGCCGAAAAGCGTCTTGAAGAACTTC
GGCGAGGTGAGAGTGATACCGTTTCGCTGGCCGAGCTGATGACGCGTTATGGCGTGGAGAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References