Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE-HTH_26
Location 632223..632825 Replicon chromosome
Accession NZ_CP020947
Organism Rhizobium sp. CIAT894

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag RHEC894_RS03115 Protein ID WP_085738839.1
Coordinates 632223..632468 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag RHEC894_RS03120 Protein ID WP_085736095.1
Coordinates 632478..632825 (+) Length 116 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RHEC894_RS03075 627467..627898 + 432 WP_085736087.1 DUF2948 family protein -
RHEC894_RS03080 628008..629306 + 1299 WP_085736089.1 histidinol dehydrogenase -
RHEC894_RS03085 629311..629784 + 474 WP_085736091.1 UPF0262 family protein -
RHEC894_RS03090 629790..630266 + 477 WP_085736093.1 low molecular weight phosphatase family protein -
RHEC894_RS03095 630390..630608 + 219 WP_003545338.1 translation initiation factor IF-1 -
RHEC894_RS03100 630666..631286 + 621 WP_028757471.1 Maf-like protein -
RHEC894_RS03105 631325..631537 + 213 WP_085738838.1 DNA gyrase inhibitor YacG -
RHEC894_RS03115 632223..632468 + 246 WP_085738839.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
RHEC894_RS03120 632478..632825 + 348 WP_085736095.1 helix-turn-helix transcriptional regulator Antitoxin
RHEC894_RS03125 633169..634146 + 978 WP_085736096.1 phosphodiester glycosidase family protein -
RHEC894_RS03130 634313..635356 - 1044 WP_010068938.1 saccharopine dehydrogenase NADP-binding domain-containing protein -
RHEC894_RS03135 635461..636057 + 597 WP_085738840.1 TetR/AcrR family transcriptional regulator -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(63-114)


Sequences


Toxin        


Download         Length: 82 a.a.        Molecular weight: 9037.61 Da        Isoelectric Point: 10.6821

>T75758 WP_085738839.1 NZ_CP020947:632223-632468 [Rhizobium sp. CIAT894]
MKKIAYSKAAVKALRKMQQKRAAAIVAKVEAFANGETVDLKKLQGSEFFRIRVGQDRVIIDDQTMQVLVVKAGPRGDVYN
E

Download         Length: 246 bp

>T75758 NZ_CP020947:632223-632468 [Rhizobium sp. CIAT894]
ATGAAAAAGATCGCGTACAGCAAAGCTGCCGTGAAGGCACTCCGCAAAATGCAGCAGAAGCGCGCGGCCGCGATCGTAGC
CAAGGTAGAAGCCTTCGCCAATGGCGAGACAGTCGACCTCAAGAAGCTGCAAGGCAGCGAATTTTTTCGCATTCGCGTTG
GGCAGGACCGGGTCATCATAGACGACCAGACTATGCAGGTCTTGGTCGTCAAAGCTGGCCCACGTGGCGATGTTTATAAC
GAATAG

Antitoxin


Download         Length: 116 a.a.        Molecular weight: 12641.20 Da        Isoelectric Point: 4.2126

>AT75758 WP_085736095.1 NZ_CP020947:632478-632825 [Rhizobium sp. CIAT894]
MGEIQKLTIDGKGYVLLSEDDYQDLVDISDARAAKARIDDGEETWPQDVVEALIAGEDPVRVFRKHRGISIKELAEKAGL
SQPYLSEIETGKKEGSLDALKAIARTLEVDLDDLA

Download         Length: 348 bp

>AT75758 NZ_CP020947:632478-632825 [Rhizobium sp. CIAT894]
ATGGGTGAAATCCAGAAACTAACCATCGACGGCAAGGGATACGTGCTGCTTTCCGAAGATGATTATCAGGACCTTGTCGA
TATCAGCGACGCGCGCGCAGCAAAGGCGCGCATCGACGATGGCGAAGAAACCTGGCCTCAAGACGTCGTCGAGGCGCTGA
TCGCCGGTGAAGATCCTGTCCGCGTGTTCCGTAAGCATCGCGGCATCAGCATCAAGGAACTGGCTGAAAAGGCCGGGCTC
TCGCAGCCTTATCTTTCCGAAATCGAGACTGGAAAGAAAGAGGGCTCCCTAGATGCTCTAAAGGCGATCGCTCGTACGCT
GGAAGTCGACCTTGACGATCTGGCTTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References