Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3397946..3398563 Replicon chromosome
Accession NZ_CP020943
Organism Pantoea ananatis strain PNA 97-1R

Toxin (Protein)


Gene name Hha Uniprot ID D4GLR0
Locus tag B9Q16_RS16280 Protein ID WP_013024903.1
Coordinates 3398348..3398563 (+) Length 72 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID A0A8A4KA49
Locus tag B9Q16_RS16275 Protein ID WP_015700827.1
Coordinates 3397946..3398323 (+) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9Q16_RS16245 3394231..3394485 + 255 WP_014606427.1 type B 50S ribosomal protein L31 -
B9Q16_RS16250 3394497..3394637 + 141 WP_014606428.1 type B 50S ribosomal protein L36 -
B9Q16_RS16255 3394697..3395575 - 879 WP_013024908.1 metal ABC transporter substrate-binding protein -
B9Q16_RS16260 3395588..3396427 - 840 WP_013024907.1 metal ABC transporter permease -
B9Q16_RS16265 3396424..3397092 - 669 WP_014606429.1 ABC transporter ATP-binding protein -
B9Q16_RS16270 3397446..3397799 + 354 WP_041455996.1 hypothetical protein -
B9Q16_RS16275 3397946..3398323 + 378 WP_015700827.1 Hha toxicity modulator TomB Antitoxin
B9Q16_RS16280 3398348..3398563 + 216 WP_013024903.1 hemolysin expression modulator Hha Toxin
B9Q16_RS16290 3398961..3399272 + 312 WP_014606432.1 MGMT family protein -
B9Q16_RS16295 3399321..3399878 - 558 WP_019106636.1 YbaY family lipoprotein -
B9Q16_RS16300 3400071..3400934 + 864 WP_014606434.1 acyl-CoA thioesterase II -
B9Q16_RS16305 3400981..3402270 - 1290 WP_072137846.1 ammonium transporter AmtB -
B9Q16_RS16310 3402305..3402643 - 339 WP_013024898.1 P-II family nitrogen regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(12-68)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 72 a.a.        Molecular weight: 8552.98 Da        Isoelectric Point: 9.4825

>T75755 WP_013024903.1 NZ_CP020943:3398348-3398563 [Pantoea ananatis]
MNKTLTKTDYLMRLRRCRSIDTLERVIEKNKYELPDEELAVFYSAADHRLAELTMNKLYDKVPVSVWKFVR

Download         Length: 216 bp

>T75755 NZ_CP020943:3398348-3398563 [Pantoea ananatis]
ATGAACAAAACCCTAACTAAAACTGATTATTTGATGCGACTGAGGCGCTGTCGTTCTATTGACACGCTGGAACGCGTGAT
TGAAAAAAATAAGTACGAATTACCCGATGAAGAATTAGCAGTATTTTACTCAGCAGCCGATCACCGCCTGGCTGAACTGA
CGATGAACAAGCTCTATGACAAAGTCCCGGTGTCAGTCTGGAAATTTGTACGCTAA

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14722.35 Da        Isoelectric Point: 4.3976

>AT75755 WP_015700827.1 NZ_CP020943:3397946-3398323 [Pantoea ananatis]
MDEYSPKRHDIAQLKYLCENLFDDSMATLTDSHHGWVNDPTAESNLQLNDLIEHIASFTMNYKIKHVEDEALITQIDEYL
DDTFMLFSNYSVNTQDLQRWQRSAKRLFNVFTEECAFLQQPSHSL

Download         Length: 378 bp

>AT75755 NZ_CP020943:3397946-3398323 [Pantoea ananatis]
ATGGACGAATACTCACCGAAACGGCATGATATTGCCCAGCTTAAATACTTGTGTGAGAATCTGTTTGACGACAGCATGGC
GACATTAACTGACAGTCATCACGGCTGGGTTAATGACCCCACTGCCGAAAGCAATTTACAGCTAAACGATTTGATTGAGC
ACATCGCCTCTTTCACCATGAATTACAAAATTAAGCACGTTGAAGACGAAGCACTGATTACCCAAATCGATGAATATCTT
GATGATACCTTTATGCTGTTTAGCAACTACAGTGTAAATACTCAGGATCTTCAGCGCTGGCAACGCTCAGCGAAACGTTT
ATTTAATGTGTTTACTGAAGAGTGCGCTTTTCTTCAACAGCCAAGCCATTCATTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References