Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 2334504..2335852 Replicon chromosome
Accession NZ_CP020943
Organism Pantoea ananatis strain PNA 97-1R

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag B9Q16_RS11200 Protein ID WP_104933393.1
Coordinates 2334743..2335852 (+) Length 370 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag B9Q16_RS11195 Protein ID WP_013025828.1
Coordinates 2334504..2334743 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9Q16_RS11180 2330096..2331484 + 1389 WP_014605798.1 MFS transporter -
B9Q16_RS11185 2331507..2333882 + 2376 WP_104933394.1 glycoside hydrolase family 3 C-terminal domain-containing protein -
B9Q16_RS11190 2333946..2334389 - 444 WP_013025829.1 GNAT family N-acetyltransferase -
B9Q16_RS11195 2334504..2334743 + 240 WP_013025828.1 type II toxin-antitoxin system antitoxin HipB Antitoxin
B9Q16_RS11200 2334743..2335852 + 1110 WP_104933393.1 HipA domain-containing protein Toxin
B9Q16_RS11205 2335898..2336314 - 417 WP_072138780.1 GFA family protein -
B9Q16_RS11215 2336765..2338633 - 1869 WP_013025825.1 low affinity potassium transporter Kup -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(132-328)

Antitoxin

Cro/C1-type helix-turn-helix domain

(13-63)


Sequences

Toxin        


Download         Length: 370 a.a.        Molecular weight: 40970.28 Da        Isoelectric Point: 7.4556

>T75754 WP_104933393.1 NZ_CP020943:2334743-2335852 [Pantoea ananatis]
MAKLIAWINGERTGTLTLHHNGALHFQYDANWLQHPLARPLSLSLPLQRAAMHSEKVVHFFENLLFPSTLIEKDFYPTHP
IKSCEVFATLQKVGHTLPGALSLLPAKRQPVASDQATHSVFSPADEAQQFDIDNAYLCLSLARELTIPVPDAVLVHENGI
RKLRTERYDRRWRHDGQHLYHLPEEDVCQALGVPLSGRDEQQGGPGIDDIMALLMGSSSAMKDREDMMRCLVFQWLTGIT
RVNAKHLSLLIARGGSFRLAPFKHLLSACPGLSLRTTDRQDFQLAMGVTGPEGKQHHIDAIRPAHFLALAGSVGFSQAAM
RQILAAFVPGLPAAIVKVRDSLPDDYPLTLADAVFSHAMMMLERVRQAI

Download         Length: 1110 bp

>T75754 NZ_CP020943:2334743-2335852 [Pantoea ananatis]
ATGGCAAAGCTCATTGCCTGGATAAACGGCGAGCGTACGGGAACGCTGACGCTGCATCACAACGGCGCGCTACATTTCCA
GTATGACGCCAACTGGCTTCAGCATCCGCTTGCCAGACCTCTCTCGCTTTCGTTGCCCTTACAGCGCGCCGCGATGCATT
CTGAGAAAGTCGTGCACTTTTTCGAAAACCTTCTCTTTCCCAGCACTTTGATCGAAAAGGATTTTTACCCGACTCACCCG
ATAAAATCCTGTGAGGTGTTTGCAACATTGCAGAAAGTGGGACACACATTACCCGGGGCGCTCAGTCTGCTGCCGGCAAA
GCGGCAGCCCGTCGCGTCGGACCAGGCAACGCACAGCGTCTTCAGCCCCGCCGATGAGGCACAGCAGTTCGATATCGATA
ATGCGTATCTGTGTCTGTCCCTGGCCCGGGAGCTAACTATCCCGGTGCCGGATGCCGTGTTAGTTCATGAGAACGGCATC
CGTAAATTGAGAACAGAACGATACGATCGCCGTTGGCGTCACGACGGACAACACCTTTATCATCTTCCTGAAGAAGACGT
GTGTCAGGCGCTCGGCGTGCCGCTCTCTGGCCGCGATGAGCAGCAGGGCGGTCCGGGAATTGATGACATCATGGCCTTGC
TGATGGGCTCAAGCTCCGCCATGAAAGACCGTGAGGATATGATGCGCTGTCTGGTATTTCAGTGGCTGACGGGCATCACA
CGCGTCAACGCTAAACATCTCTCGCTGCTGATTGCTCGCGGTGGCAGCTTCCGGCTCGCGCCTTTTAAGCATCTTCTTTC
CGCCTGCCCGGGCCTTTCTCTGCGCACAACAGACAGACAGGATTTCCAGCTGGCGATGGGCGTGACAGGCCCTGAGGGCA
AACAGCATCACATTGACGCGATTCGGCCCGCGCATTTTCTTGCCCTTGCGGGGAGCGTGGGGTTCAGTCAGGCAGCGATG
CGGCAGATACTCGCGGCCTTTGTTCCGGGCTTGCCTGCCGCGATTGTTAAGGTGCGGGACAGCCTGCCCGATGATTATCC
CCTGACGCTCGCCGATGCGGTTTTCAGCCACGCAATGATGATGCTGGAAAGGGTGCGCCAGGCGATCTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8746.94 Da        Isoelectric Point: 7.2012

>AT75754 WP_013025828.1 NZ_CP020943:2334504-2334743 [Pantoea ananatis]
MIYSPRQLANQVRLLRQQNGWTQVELAKKVGLKQATLSHFENAPDTTSLATLFKILQALDLALSLHENSASSAPAEDAW

Download         Length: 240 bp

>AT75754 NZ_CP020943:2334504-2334743 [Pantoea ananatis]
ATGATTTACAGTCCCCGCCAGTTGGCGAATCAGGTCAGGCTATTGCGGCAGCAAAACGGCTGGACCCAGGTCGAACTGGC
GAAAAAAGTGGGCCTGAAACAGGCAACCCTGTCTCACTTCGAAAATGCCCCGGATACAACCTCACTGGCAACGTTGTTCA
AAATCTTACAGGCGCTCGATCTTGCTCTGTCGCTTCATGAAAACAGCGCATCCTCAGCCCCGGCTGAGGATGCCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References