Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 2019472..2020207 Replicon chromosome
Accession NZ_CP020943
Organism Pantoea ananatis strain PNA 97-1R

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag B9Q16_RS09710 Protein ID WP_089517249.1
Coordinates 2019472..2019864 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag B9Q16_RS09715 Protein ID WP_104933433.1
Coordinates 2019854..2020207 (+) Length 118 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9Q16_RS09695 2014770..2015942 - 1173 WP_013026120.1 FMNH2-dependent alkanesulfonate monooxygenase -
B9Q16_RS09700 2016219..2018105 + 1887 WP_072138116.1 aliphatic sulfonate ABC transporter substrate-binding protein -
B9Q16_RS09705 2018200..2019147 + 948 WP_015700094.1 sulfonate ABC transporter substrate-binding protein -
B9Q16_RS09710 2019472..2019864 + 393 WP_089517249.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
B9Q16_RS09715 2019854..2020207 + 354 WP_104933433.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
B9Q16_RS09730 2020759..2021298 - 540 WP_022623267.1 peptide-methionine (S)-S-oxide reductase MsrA -
B9Q16_RS09735 2021661..2022728 - 1068 WP_013026114.1 two-component system sensor histidine kinase PmrB -
B9Q16_RS09740 2022725..2023411 - 687 WP_013026113.1 two-component system response regulator PmrA -
B9Q16_RS09745 2024298..2025086 + 789 WP_013026112.1 trehalose-phosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(6-125)

Antitoxin

Cro/C1-type helix-turn-helix domain

(56-99)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14959.25 Da        Isoelectric Point: 10.1482

>T75745 WP_089517249.1 NZ_CP020943:2019472-2019864 [Pantoea ananatis]
MGFTLYVHKRFDRVFKKTRLTDSVLCYAAGDVFTGVFEADLGGGVIKKRLALHQGKRGGARTVIFFRQGTNLVYYDGWVK
NLSRKYAKEIDEDQLDTYRDVARMFFRANSEVMSLLVRSGMVREVKCNEN

Download         Length: 393 bp

>T75745 NZ_CP020943:2019472-2019864 [Pantoea ananatis]
ATGGGTTTTACGCTTTATGTTCATAAACGTTTTGACAGAGTGTTTAAAAAAACGCGTCTGACAGACAGCGTCCTGTGTTA
CGCAGCAGGTGACGTTTTTACTGGCGTGTTTGAGGCTGACTTAGGCGGTGGCGTTATTAAAAAGCGTCTTGCTCTTCACC
AAGGCAAGCGTGGCGGCGCGCGAACGGTCATCTTCTTCAGACAAGGCACCAACCTGGTTTATTACGATGGATGGGTTAAA
AACTTGTCGAGGAAATACGCTAAAGAAATCGATGAAGATCAGCTGGATACCTACAGGGATGTGGCAAGAATGTTTTTCCG
TGCAAATAGTGAAGTGATGAGCCTGCTCGTCAGAAGCGGAATGGTCAGAGAGGTTAAATGTAATGAAAACTGA

Antitoxin


Download         Length: 118 a.a.        Molecular weight: 13111.16 Da        Isoelectric Point: 6.4825

>AT75745 WP_104933433.1 NZ_CP020943:2019854-2020207 [Pantoea ananatis]
MKTEPAELSELLEDAKAFHALGLATDEELESIAKRAKNRELRARIASVKPMTATEIKDVRMRWGMSQSLVALSFGMTVDS
VSKWERGEITPSPPVMRMLQLLRDNGPELFTSKHEGI

Download         Length: 354 bp

>AT75745 NZ_CP020943:2019854-2020207 [Pantoea ananatis]
ATGAAAACTGAACCCGCCGAATTGAGTGAACTACTTGAAGATGCGAAAGCGTTTCACGCGTTAGGACTGGCAACAGATGA
AGAATTGGAGTCCATAGCAAAGCGCGCAAAAAATCGTGAACTCCGTGCCCGTATTGCATCAGTAAAGCCCATGACAGCAA
CTGAAATCAAAGACGTGCGCATGCGTTGGGGAATGTCGCAATCGCTTGTGGCGCTCTCATTTGGCATGACGGTCGATAGC
GTATCGAAATGGGAGCGAGGTGAAATCACACCGAGCCCACCGGTGATGCGGATGCTGCAACTCCTTCGCGATAACGGCCC
TGAACTCTTTACCTCTAAGCATGAAGGTATCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References