75742

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4274531..4274881 Replicon chromosome
Accession NZ_CP020942
Organism Xanthomonas oryzae pv. oryzae strain PXO61

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag B9W05_RS21010 Protein ID WP_011257368.1
Coordinates 4274747..4274881 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag B9W05_RS21005 Protein ID WP_011407410.1
Coordinates 4274531..4274683 (+) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9W05_RS20980 (B9W05_20660) 4270811..4271494 - 684 WP_011257363.1 dTMP kinase -
B9W05_RS25825 4271974..4272516 - 543 Protein_3817 GTPase -
B9W05_RS20995 (B9W05_20680) 4272513..4272968 - 456 Protein_3818 hypothetical protein -
B9W05_RS25830 4272960..4273178 - 219 Protein_3819 hypothetical protein -
B9W05_RS21000 (B9W05_20685) 4273500..4274423 + 924 WP_011407409.1 arginase -
B9W05_RS21005 (B9W05_20690) 4274531..4274683 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
B9W05_RS21010 (B9W05_20695) 4274747..4274881 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
B9W05_RS21015 (B9W05_20700) 4275122..4275331 + 210 WP_011407411.1 CsbD family protein -
B9W05_RS21020 (B9W05_20705) 4275500..4276789 + 1290 WP_069959696.1 tryptophan--tRNA ligase -
B9W05_RS21025 (B9W05_20710) 4276920..4277864 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T75742 WP_011257368.1 NZ_CP020942:4274747-4274881 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T75742 NZ_CP020942:4274747-4274881 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT75742 WP_011407410.1 NZ_CP020942:4274531-4274683 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT75742 NZ_CP020942:4274531-4274683 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References