Detailed information of TA system TA075739

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 1774681..1775237
• Replicon: chromosome
• Accession: NZ_CP020942
• Organism: Xanthomonas oryzae pv. oryzae strain PXO61

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: B9W05_RS08665
• Protein ID: WP_229001948.1
• Coordinates: 1774681..1774932 (-)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: B9W05_RS08670
• Protein ID: WP_011408759.1
• Coordinates: 1774959..1775237 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B9W05_RS08615 (B9W05_08500)	1770451..1771542	+	1092	WP_041182166.1	ribonuclease D	-
B9W05_RS08620 (B9W05_08505)	1771618..1771955	-	338	Protein_1585	ATP-dependent DNA ligase	-
B9W05_RS25445 (B9W05_08515)	1772237..1772413	-	177	Protein_1586	DUF3606 domain-containing protein	-
B9W05_RS08635 (B9W05_08520)	1772635..1773036	+	402	WP_011259345.1	H-NS family nucleoid-associated regulatory protein	-
B9W05_RS26010	1773467..1773595	-	129	WP_012444694.1	hypothetical protein	-
B9W05_RS25450	1773564..1773683	-	120	Protein_1589	IS3 family transposase	-
B9W05_RS08655 (B9W05_08535)	1773900..1774154	-	255	WP_223293127.1	hypothetical protein	-
B9W05_RS25455	1774223..1774420	-	198	WP_004541336.1	hypothetical protein	-
B9W05_RS08665 (B9W05_08545)	1774681..1774932	-	252	WP_229001948.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
B9W05_RS08670 (B9W05_08550)	1774959..1775237	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
B9W05_RS08675 (B9W05_08555)	1775433..1775777	-	345	WP_199285675.1	hypothetical protein	-
B9W05_RS08685 (B9W05_08565)	1776683..1777867	-	1185	WP_011408760.1	IS256-like element IS1113 family transposase	-
B9W05_RS08695 (B9W05_08570)	1778448..1779413	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
B9W05_RS08700 (B9W05_08575)	1779563..1780120	+	558	WP_011259349.1	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-81)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9603.92 Da
• Isoelectric Point: 9.9718

>T75739 WP_229001948.1 NZ_CP020942:c1774932-1774681 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Nucleotide

• Length: 252 bp

>T75739 NZ_CP020942:c1774932-1774681 [Xanthomonas oryzae pv. oryzae]
ATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGATGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGT
CCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAGAAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATT
TTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGGGATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAA
GCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT75739 WP_011408759.1 NZ_CP020942:c1775237-1774959 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT75739 NZ_CP020942:c1775237-1774959 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2