Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2520692..2520963 Replicon chromosome
Accession NZ_CP020933
Organism Escherichia coli strain HB-Coli0

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2520822..2520925 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2520692..2520963 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9W17_RS12270 2517247..2517909 - 663 WP_000944256.1 exodeoxyribonuclease X -
B9W17_RS12275 2517933..2518589 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
B9W17_RS12280 2518691..2518921 - 231 WP_000916763.1 DNA polymerase III subunit theta -
B9W17_RS12285 2519060..2519434 + 375 WP_000204699.1 CopC domain-containing protein YobA -
B9W17_RS12290 2519438..2520310 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
B9W17_RS12295 2520323..2520664 + 342 WP_000976472.1 YebY family protein -
- 2520692..2520963 - 272 - - Antitoxin
- 2520822..2520925 + 104 - - Toxin
B9W17_RS12300 2521060..2521716 + 657 WP_000812735.1 protein-serine/threonine phosphatase -
B9W17_RS12305 2521717..2521908 - 192 WP_001296140.1 YebW family protein -
B9W17_RS12310 2522013..2522249 - 237 WP_001295499.1 DUF1480 family protein -
B9W17_RS12315 2522367..2523806 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T75716 NZ_CP020933:2520822-2520925 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT75716 NZ_CP020933:c2520963-2520692 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References