Detailed information of TA system TA075698

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 4156385..4156842
• Replicon: chromosome
• Accession: NZ_CP020925
• Organism: Sphingobium yanoikuyae strain SHJ

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: BV87_RS19685
• Protein ID: WP_048939061.1
• Coordinates: 4156567..4156842 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A0J9CV54
• Locus tag: BV87_RS19680
• Protein ID: WP_048939062.1
• Coordinates: 4156385..4156567 (+)
• Length: 61 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BV87_RS19670	4151891..4154803	+	2913	WP_048939064.1	excinuclease ABC subunit UvrA	-
BV87_RS19675	4154881..4156305	+	1425	WP_048939063.1	hypothetical protein	-
BV87_RS19680	4156385..4156567	+	183	WP_048939062.1	hypothetical protein	Antitoxin
BV87_RS19685	4156567..4156842	+	276	WP_048939061.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BV87_RS19690	4157084..4158280	+	1197	WP_048939060.1	hypothetical protein	-
BV87_RS19695	4158392..4158607	+	216	WP_037512246.1	cold-shock protein	-
BV87_RS19700	4158666..4159268	-	603	WP_048939059.1	hypothetical protein	-
BV87_RS19705	4159405..4159632	+	228	WP_048939071.1	hypothetical protein	-
BV87_RS19710	4159827..4160195	+	369	WP_010336654.1	glycine zipper 2TM domain-containing protein	-
BV87_RS19715	4160259..4161191	-	933	WP_037512249.1	FAD-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10744.31 Da
• Isoelectric Point: 8.5205

>T75698 WP_048939061.1 NZ_CP020925:4156567-4156842 [Sphingobium yanoikuyae]
MPHIIWRERAREDVRTIIDYISDRNPTAALRLADLFAQVAEQLVYHPHMHRNGRVPDTREAIVTPNYILIYRVGTEAIEI
LNVKHTRQQYP

Nucleotide

• Length: 276 bp

>T75698 NZ_CP020925:4156567-4156842 [Sphingobium yanoikuyae]
ATGCCACACATCATCTGGCGCGAGAGAGCGCGGGAAGACGTGCGCACTATCATCGACTATATTTCTGATCGCAATCCGAC
GGCTGCGCTGCGCCTGGCCGACCTGTTCGCCCAAGTCGCAGAACAATTGGTCTATCATCCCCATATGCACCGCAACGGGC
GCGTTCCCGACACGCGCGAAGCGATCGTCACACCCAACTATATCCTCATCTATCGGGTCGGCACCGAAGCGATCGAAATC
CTGAACGTCAAGCACACCCGCCAGCAATATCCCTGA

Antitoxin

Protein

• Length: 61 a.a.
• Molecular weight: 6573.41 Da
• Isoelectric Point: 4.4797

>AT75698 WP_048939062.1 NZ_CP020925:4156385-4156567 [Sphingobium yanoikuyae]
MTKLTPIESEFATTEEAAAYDAWFKAEVEASLADPRPGVPHDQVMAELRAIIDAKKARQG

Nucleotide

• Length: 183 bp

>AT75698 NZ_CP020925:4156385-4156567 [Sphingobium yanoikuyae]
ATGACGAAGCTCACGCCCATCGAGTCCGAATTTGCGACGACCGAGGAGGCCGCCGCCTATGACGCTTGGTTCAAGGCGGA
GGTTGAGGCGAGCCTGGCCGATCCCCGGCCGGGCGTGCCACATGATCAGGTAATGGCCGAACTGCGCGCGATCATCGACG
CCAAGAAGGCCCGGCAAGGCTGA

Structures

Antitoxin

• AlphaFold DB: A0A0J9CV54