Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicB
Location 36831..37475 Replicon plasmid unnamed2
Accession NZ_CP020924
Organism Salmonella enterica subsp. enterica strain 16A242

Toxin (Protein)


Gene name hicA Uniprot ID A0A7L6LII1
Locus tag B6N26_RS26070 Protein ID WP_000833471.1
Coordinates 36831..37013 (+) Length 61 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID A0A7L6LHN8
Locus tag B6N26_RS26075 Protein ID WP_000466317.1
Coordinates 37038..37475 (+) Length 146 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B6N26_RS26000 31930..32253 + 324 WP_000432877.1 hypothetical protein -
B6N26_RS26005 32294..32518 + 225 WP_000866040.1 hypothetical protein -
B6N26_RS26010 32614..32838 + 225 WP_000749828.1 hypothetical protein -
B6N26_RS26015 32889..33155 + 267 WP_000702249.1 hypothetical protein -
B6N26_RS26020 33145..33387 + 243 WP_001450803.1 hypothetical protein -
B6N26_RS26030 33830..34153 + 324 WP_000432877.1 hypothetical protein -
B6N26_RS26035 34193..34417 + 225 WP_000866040.1 hypothetical protein -
B6N26_RS26040 34513..34737 + 225 WP_000749828.1 hypothetical protein -
B6N26_RS26045 34788..35054 + 267 WP_000702249.1 hypothetical protein -
B6N26_RS26050 35044..35286 + 243 WP_001450803.1 hypothetical protein -
B6N26_RS26060 35729..36058 + 330 WP_000449468.1 hypothetical protein -
B6N26_RS26065 36116..36394 + 279 WP_000545936.1 hypothetical protein -
B6N26_RS26070 36831..37013 + 183 WP_000833471.1 type II toxin-antitoxin system HicA family toxin Toxin
B6N26_RS26075 37038..37475 + 438 WP_000466317.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
B6N26_RS26080 37504..38208 - 705 WP_001279865.1 hypothetical protein -
B6N26_RS26085 38205..38966 - 762 WP_001097937.1 conjugal transfer protein TraL -
B6N26_RS26090 38976..39383 - 408 WP_001190619.1 hypothetical protein -
B6N26_RS26095 39729..40067 + 339 WP_000753495.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..65419 65419


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-105)

Antitoxin

Antitoxin MazE-like

(4-66)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 7836.64 Da        Isoelectric Point: 12.5781

>T75695 WP_000833471.1 NZ_CP020924:36831-37013 [Salmonella enterica subsp. enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 183 bp

>T75695 NZ_CP020924:36831-37013 [Salmonella enterica subsp. enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 146 a.a.        Molecular weight: 18731.43 Da        Isoelectric Point: 12.9614

>AT75695 WP_000466317.1 NZ_CP020924:37038-37475 [Salmonella enterica subsp. enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 438 bp

>AT75695 NZ_CP020924:37038-37475 [Salmonella enterica subsp. enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7L6LII1

Antitoxin

Source ID Structure
AlphaFold DB A0A7L6LHN8

References